Effect of preoperative flupirtine on post operative pain after total abdominal hysterectomy.
Phase 4
Completed
- Conditions
- Health Condition 1: null- Patients scheduled for total abdominal hysterectomy.
- Registration Number
- CTRI/2013/12/004226
- Lead Sponsor
- Government Medical College and Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
50 female patients of ASA physical status I & II, aged between 30 to 60 years, having weight between 50-80 kg and scheduled for total abdominal hysterectomy will be enrolled.
Exclusion Criteria
Patients having ASA > II
BMI > 30 kg.m-2
Patients having history of substance abuse.
Patients having inability to use PCA pump.
Allergy to study drug morphine, flupirtine.
Known significant abnormalities of renal or hepatic function.
Patients on warfarin.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method morphine consumptionTimepoint: At 0, 2,4,6,8,12,24,48 hours after surgery (0 hour being the time of admission to post anaesthesia care unit(PACU) when the first pain measurement will be taken).
- Secondary Outcome Measures
Name Time Method mean arterial pressure (MAP), pulse rate (PR), respiratory rate (RR), Visual Analogue Score(VAS) for rest pain, VAS on coughing, nausea or vomiting, sedation,pruritis,shiveringTimepoint: At 0, 2,4,6,8,12,24,48 hours after surgery