Endovascular treatmenT for Acute Ischemic Stroke in China (DETECT2-China)

Completed

• Conditions: Stroke, Ischemic

• Registration Number: NCT05092139
• Lead Sponsor: General Hospital of Shenyang Military Region

Brief Summary

This is a prospective real world registry study, aiming to explore the effectiveness and safety of endovascular treatment of acute ischemic stroke in a Chinese population.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-10-13
• Study First Submitted QC: 2021-10-13
• Study First Posted: 2021-10-25
• Study Start: 2022-01-21
• Primary Completion: 2025-01-10
• Study Completion: 2025-01-10
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-14
• Last Update Posted: 2025-03-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

• Age: ≥ 18;
• Ischemic stroke confirmed by head CT or MRI;
• Patients receiving endovascular treatment;
• First ever stroke or pre-stroke mRS≤2;
• signed informed consent.

Exclusion Criteria

• Prestroke mRS≥3;
• Other serious illness that would confound the clinical outcome at 90 days;
• Unavailable neuroimaging data;
• Other unsuitable conditions judged by the investigator

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients with modified Rankin Score 0 to 2	Day 90	the minimum and maximum values of modified Rankin Score are 0 and 6, respectively; higher score mean a worse outcome

Secondary Outcome Measures

Name	Time	Method
Proportion of death	7 days	death due to any cause
Proportion of patients with modified Rankin Score 0 to 1	Day 90	the minimum and maximum values of modified Rankin Score are 0 and 6, respectively; higher score mean a worse outcome
Distribution of modified Rankin Score	Day 90	the minimum and maximum values of modified Rankin Score are 0 and 6, respectively; higher score mean a worse outcome
Proportion of symptomatic intracranial hemorrhage (sICH)	48 hours	sICH was defined as 4 or more increase in NIHSS caused by hemorrhage
Changes in National Institute of Health stroke scale (NIHSS)	24 hours, 48 hours, and 2 weeks	the minimum and maximum values of NIHSS are 0 and 24, respectively; higher NIHSS mean a worse outcome

Trial Locations

Locations (1)

Hui-Sheng Chen; 🇨🇳 ShenYang, Liaoning, China