Cardio Training of Older Adults With Central Obesity
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Change in visceral adipose tissue mass
研究概览
简要总结
Given the increasing prevalence of obesity, there is an urgent need to find better strategies to promote physical activity in the community. The present study will invite 70-year-olds with central (abdominal) obesity to participate in a 10-week aerobic exercise program. Participants will be randomly assigned to one of two equally large groups. The first group will complete the exercise program in instructor-led groups. The second group will complete the program at home with the help of an on-line video.
详细描述
Central obesity means having a lot visceral fat, that is, fat located in the abdominal cavity. Visceral fat is a well-established risk factor for cardiovascular disease and all-cause mortality.
Participants will be recruited from the Healthy Ageing Initiative (HAI), an ongoing population-based study that invites all 70-year-olds in Umeå, Sweden, to a health examination. The exercise program will focus is on station-based aerobic exercises and resistance exercises, predominantly with participants' own body weight as resistance. The program is progressive, starting at a moderate pace so that participants learn to perform the exercises properly. The intensity will be aimed at 60-80% of maximal exhaustion, and each exercise bout will last 60 seconds with 20 seconds of rest between bouts. The program was developed by seniors in the bachelor's program in exercise physiology at Umeå University, Sweden.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
The Data Analyst will also be masked.
入排标准
- 年龄范围
- 70 Years 至 70 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participated in the Healthy Ageing Initiative (a population-based intervention study in Umeå, Sweden)
- •Visceral adipose tissue mass >1 kg (women) or >2 kg (men)
排除标准
- •Physical disability that affects ability to perform the exercises
- •Heart failure or severe degenerative condition (e.g. malignant cancer or multiple sclerosis)
- •Myocardial infarction or stroke in the past year
- •Heart condition that can worsen with aerobic exercise (e.g. angina)
研究组 & 干预措施
Control group
Weeks 1-10: no intervention. Weeks 11-20: no intervention. Weeks 21-31: exercise program at home.
干预措施: 10-week aerobic exercise program (Other)
Intervention Group
Weeks 1-10: exercise program in group. Weeks 11-20: no intervention. Weeks 21-31: no intervention.
干预措施: 10-week aerobic exercise program (Other)
结局指标
主要结局
Change in visceral adipose tissue mass
时间窗: 0, 10, 20, and 31 weeks
Mass (g) measured using Lunar iDXA with CoreScan application (GE Healthcare, Wauwatosa, WI, USA).
次要结局
- Change in body composition(0, 10, 20, and 31 weeks)
- Change in blood-lipid profile(0, 10, 20, and 31 weeks)
- Change in self-reported physical activity(0, 10, 20, and 31 weeks)
- Change in health-related quality of life(0, 10, 20, and 31 weeks)
- Change in Microbiota composition(0, 10, 20, and 31 weeks)
- Change in concentration of inflammatory markers(0, 10, 20, and 31 weeks)
- Change in dietary habits(0, 10, 20, and 31 weeks)
- Change in physical capacity(0, 10, 20, and 31 weeks)
- Change in Body Mass Index (kg/m^2)(0, 10, 20, and 31 weeks)
- Change in blood pressure (mmHg)(0, 10, 20, and 31 weeks)
- Change in fasting blood glucose(0, 10, 20, and 31 weeks)
- Change in isometric muscle strength(0, 10, 20, and 31 weeks)
- Change in resting metabolic rate(0, 10, 20, and 31 weeks)
研究者
Anna Nordström
Adjunct Professor
Region Västerbotten