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Clinical Trials/NCT03450655
NCT03450655
Unknown
Not Applicable

Cardio Training of Older Adults With Central Obesity

Region Västerbotten1 site in 1 country80 target enrollmentFebruary 9, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Visceral Obesity
Sponsor
Region Västerbotten
Enrollment
80
Locations
1
Primary Endpoint
Change in visceral adipose tissue mass
Last Updated
8 years ago

Overview

Brief Summary

Given the increasing prevalence of obesity, there is an urgent need to find better strategies to promote physical activity in the community. The present study will invite 70-year-olds with central (abdominal) obesity to participate in a 10-week aerobic exercise program. Participants will be randomly assigned to one of two equally large groups. The first group will complete the exercise program in instructor-led groups. The second group will complete the program at home with the help of an on-line video.

Detailed Description

Central obesity means having a lot visceral fat, that is, fat located in the abdominal cavity. Visceral fat is a well-established risk factor for cardiovascular disease and all-cause mortality. Participants will be recruited from the Healthy Ageing Initiative (HAI), an ongoing population-based study that invites all 70-year-olds in Umeå, Sweden, to a health examination. The exercise program will focus is on station-based aerobic exercises and resistance exercises, predominantly with participants' own body weight as resistance. The program is progressive, starting at a moderate pace so that participants learn to perform the exercises properly. The intensity will be aimed at 60-80% of maximal exhaustion, and each exercise bout will last 60 seconds with 20 seconds of rest between bouts. The program was developed by seniors in the bachelor's program in exercise physiology at Umeå University, Sweden.

Registry
clinicaltrials.gov
Start Date
February 9, 2018
End Date
September 28, 2018
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Anna Nordström

Adjunct Professor

Region Västerbotten

Eligibility Criteria

Inclusion Criteria

  • Participated in the Healthy Ageing Initiative (a population-based intervention study in Umeå, Sweden)
  • Visceral adipose tissue mass \>1 kg (women) or \>2 kg (men)

Exclusion Criteria

  • Physical disability that affects ability to perform the exercises
  • Heart failure or severe degenerative condition (e.g. malignant cancer or multiple sclerosis)
  • Myocardial infarction or stroke in the past year
  • Heart condition that can worsen with aerobic exercise (e.g. angina)

Outcomes

Primary Outcomes

Change in visceral adipose tissue mass

Time Frame: 0, 10, 20, and 31 weeks

Mass (g) measured using Lunar iDXA with CoreScan application (GE Healthcare, Wauwatosa, WI, USA).

Secondary Outcomes

  • Change in body composition(0, 10, 20, and 31 weeks)
  • Change in blood-lipid profile(0, 10, 20, and 31 weeks)
  • Change in self-reported physical activity(0, 10, 20, and 31 weeks)
  • Change in health-related quality of life(0, 10, 20, and 31 weeks)
  • Change in Microbiota composition(0, 10, 20, and 31 weeks)
  • Change in concentration of inflammatory markers(0, 10, 20, and 31 weeks)
  • Change in dietary habits(0, 10, 20, and 31 weeks)
  • Change in physical capacity(0, 10, 20, and 31 weeks)
  • Change in Body Mass Index (kg/m^2)(0, 10, 20, and 31 weeks)
  • Change in blood pressure (mmHg)(0, 10, 20, and 31 weeks)
  • Change in fasting blood glucose(0, 10, 20, and 31 weeks)
  • Change in isometric muscle strength(0, 10, 20, and 31 weeks)
  • Change in resting metabolic rate(0, 10, 20, and 31 weeks)

Study Sites (1)

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