Cardio Training of Older Adults With Central Obesity
- Conditions
- Visceral Obesity
- Interventions
- Other: 10-week aerobic exercise program
- Registration Number
- NCT03450655
- Lead Sponsor
- Region Västerbotten
- Brief Summary
Given the increasing prevalence of obesity, there is an urgent need to find better strategies to promote physical activity in the community. The present study will invite 70-year-olds with central (abdominal) obesity to participate in a 10-week aerobic exercise program. Participants will be randomly assigned to one of two equally large groups. The first group will complete the exercise program in instructor-led groups. The second group will complete the program at home with the help of an on-line video.
- Detailed Description
Central obesity means having a lot visceral fat, that is, fat located in the abdominal cavity. Visceral fat is a well-established risk factor for cardiovascular disease and all-cause mortality.
Participants will be recruited from the Healthy Ageing Initiative (HAI), an ongoing population-based study that invites all 70-year-olds in Umeå, Sweden, to a health examination. The exercise program will focus is on station-based aerobic exercises and resistance exercises, predominantly with participants' own body weight as resistance. The program is progressive, starting at a moderate pace so that participants learn to perform the exercises properly. The intensity will be aimed at 60-80% of maximal exhaustion, and each exercise bout will last 60 seconds with 20 seconds of rest between bouts. The program was developed by seniors in the bachelor's program in exercise physiology at Umeå University, Sweden.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 80
- Participated in the Healthy Ageing Initiative (a population-based intervention study in Umeå, Sweden)
- Visceral adipose tissue mass >1 kg (women) or >2 kg (men)
- Physical disability that affects ability to perform the exercises
- Heart failure or severe degenerative condition (e.g. malignant cancer or multiple sclerosis)
- Myocardial infarction or stroke in the past year
- Heart condition that can worsen with aerobic exercise (e.g. angina)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Intervention Group 10-week aerobic exercise program Weeks 1-10: exercise program in group. Weeks 11-20: no intervention. Weeks 21-31: no intervention. Control group 10-week aerobic exercise program Weeks 1-10: no intervention. Weeks 11-20: no intervention. Weeks 21-31: exercise program at home.
- Primary Outcome Measures
Name Time Method Change in visceral adipose tissue mass 0, 10, 20, and 31 weeks Mass (g) measured using Lunar iDXA with CoreScan application (GE Healthcare, Wauwatosa, WI, USA).
- Secondary Outcome Measures
Name Time Method Change in health-related quality of life 0, 10, 20, and 31 weeks As measured by RAND-36
Change in self-reported physical activity 0, 10, 20, and 31 weeks Assessed using IPAQ-SF
Change in concentration of inflammatory markers 0, 10, 20, and 31 weeks Change in body composition 0, 10, 20, and 31 weeks Mass (g) measured using Lunar iDXA with CoreScan application (GE Healthcare, Wauwatosa, WI, USA)
Change in blood-lipid profile 0, 10, 20, and 31 weeks Change in Microbiota composition 0, 10, 20, and 31 weeks Fecal samples are taken and bacterial DNA is sequenced to determine bacterial composition
Change in dietary habits 0, 10, 20, and 31 weeks 85 item food frequency questionnaire
Change in physical capacity 0, 10, 20, and 31 weeks Measured using Åstrands Submaximal Test, performed on an electrically braked ergometer bicycle
Change in Body Mass Index (kg/m^2) 0, 10, 20, and 31 weeks Change in blood pressure (mmHg) 0, 10, 20, and 31 weeks Taken after 15 min of rest
Change in fasting blood glucose 0, 10, 20, and 31 weeks Veinous blood samples taken after \> 4 h of fasting
Change in isometric muscle strength 0, 10, 20, and 31 weeks Measured in non-dominant hand with dynamometer (Jamar, Lafayette Instrument, USA). The better of two successive trials will be recorded.
Change in resting metabolic rate 0, 10, 20, and 31 weeks As measured by indirect calorimetry
Trial Locations
- Locations (1)
Livsmedicin (LIFE)
🇸🇪Umeå, Västerbotten, Sweden