The Efficacy Of Complete Mesocolic Excision With Central Vessel Ligation Technique On Lymph Nodes And Safety Margins Compared With Conventional Surgery For Colon Cancer Treatment

Not Applicable

• Conditions: Cancer Colon
• Interventions: Procedure: conventional surgery of cancer colon; Procedure: Total Mesocolic Excision with Central Vessel Ligation

• Registration Number: NCT04079946
• Lead Sponsor: Assiut University

Brief Summary

Cancer Colon is one of the major public health problems worldwide. Complete eradication of the tumor with no recurrence or residual masses is a challenge which faces all the surgeons and medical staff all over the world. A lot of techniques were used to ensure 100 % eradication of the tumor and to cure the patients from cancer. Total Mesocolic Excision with Central Vessel Ligation is one of the recent techniques used for colon cancer surgeries. Here in the research the investigators answer the question of how this technique is superior and more beneficial in complete eradication of the tumor than the conventional surgery for colon cancer

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-08-29
• Status Verified: 2019-09
• Study First Submitted QC: 2019-09-03
• Last Update Submitted: 2019-09-04
• Study First Posted: 2019-09-06
• Last Update Posted: 2019-09-06
• Study Start: 2019-10-01
• Primary Completion: 2020-12-31
• Study Completion: 2021-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• • Adult male and female Age of or above 18 years.

  • Tumor localization at the caecum, ascending colon, transverse colon, descending colon, sigmoid colon or rectosigmoid on preoperative endoscopy and radiographic imaging [barium enema or computed tomography (CT)]
  • No history of familial adenomatous polyposis, ulcerative colitis or Crohn's disease
  • Written informed consent

Exclusion Criteria

• • Contraindications to major surgery and American Society of Anaesthesiologists (ASA) Physical Status scoring 4 which means extreme systemic disorders which have already become an eminent threat to life regardless of the type of treatment.

  • Infectious disease requiring treatment.
  • Pregnant women
  • Use of systemic steroids.
  • Severe pulmonary emphysema or pulmonary fibrosis

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
patients had conventional surgery before	conventional surgery of cancer colon	-
patients for whom Complete mesocolic excision will be done	Total Mesocolic Excision with Central Vessel Ligation	-

Primary Outcome Measures

Name	Time	Method
Lymph nodes harvest	Two years	Number of retrieved lymph nodes can be extracted by this technique