Long-Term Study That Measures the Safety and Efficacy of Deucravacitinib (BMS-986165) in Participants With Psoriasis
- Registration Number
- NCT04036435
- Lead Sponsor
- Bristol-Myers Squibb
- Brief Summary
The main purpose of this study is to characterize the long-term safety and efficacy of the drug Deucravacitinib (BMS-986165) in patients who have been previously enrolled in an applicable Phase 3 psoriasis study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 1452
- Completion of the protocol-required treatment period in an applicable study of BMS-986165 in moderate-to-severe psoriasis
- Women must not be pregnant, lactating, or breastfeeding
- Any disease or medical condition that the investigator feels that would make the patient unsuitable for this study.
- To be eligible for the study, a participant must not have active signs or symptoms of tuberculosis (TB) as judged by the investigator.
Other protocol-defined inclusion/exclusion criteria apply
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description BMS-986165 BMS-986165 -
- Primary Outcome Measures
Name Time Method Incidence of Adverse Events (AEs) Up to 244 weeks Incidence of Serious Adverse Events (SAEs) Up to 244 weeks
- Secondary Outcome Measures
Name Time Method Psoriasis Area and Severity Index (PASI) 75 response Up to 240 weeks static Physician Global Assessment (sPGA) 0/1 response Up to 240 weeks
Trial Locations
- Locations (270)
First OC Dermatology & Belle-Aimee Skincare Clinic Fountain Valley
🇺🇸Fountain Valley, California, United States
Local Institution - 0007
🇺🇸Miami Lakes, Florida, United States
Radiant Research - Anderson
🇺🇸Anderson, South Carolina, United States
Local Institution - 0015
🇺🇸Dallas, Texas, United States
Menter Dermatology Research Institute
🇺🇸Dallas, Texas, United States
Interspond - Houston Center for Clinical Research
🇺🇸Sugar Land, Texas, United States
Local Institution - 0051
🇰🇷Seongnam-si, Korea, Republic of
Local Institution - 0149
🇵🇱Gdansk, Poland
Krakowskie Centrum Medyczne
🇵🇱Krakow, Poland
Solumed Centrum Medyczne
🇵🇱Poznan, Poland
Local Institution - 0184
🇷🇺Smolensk, Russian Federation
Hospital Universitario Cruces
🇪🇸Barakaldo, Spain
Local Institution - 0227
🇪🇸Malaga, Spain
Synexus - Lancashire Clinical Research Centre
🇬🇧Chorley, United Kingdom
MAC Clinical Research - Blackpool
🇬🇧Lancashire, United Kingdom
Radiant Research - Columbus
🇺🇸Columbus, Ohio, United States
Local Institution - 0282
🇺🇸Pittsburgh, Pennsylvania, United States
Tufts Medical Center
🇺🇸Boston, Massachusetts, United States
Local Institution - 0291
🇺🇸Boston, Massachusetts, United States
Center for Clinical Studies - Texas Medical Center
🇺🇸Houston, Texas, United States
International Dermatology Research
🇺🇸Miami, Florida, United States
Well Pharma Medical Research
🇺🇸Miami, Florida, United States
Local Institution - 0216
🇺🇸Miami, Florida, United States
Dawes Fretzin Dermatology Group
🇺🇸Indianapolis, Indiana, United States
University of California San Diego Health Systems
🇺🇸San Diego, California, United States
University Dermatology Group
🇺🇸San Diego, California, United States
Dermatology Clinical Research Center of San Antonio
🇺🇸San Antonio, Texas, United States
Associated Skin Care Specialists - Minnesota Clinical Study Center
🇺🇸New Brighton, Minnesota, United States
Local Institution - 0247
🇦🇺Perth, Western Australia, Australia
Alliance Dermatology and Mohs Center - Phoenix
🇺🇸Phoenix, Arizona, United States
Arizona Research Center
🇺🇸Phoenix, Arizona, United States
Clinical Trials of America - Monroe
🇺🇸Monroe, Louisiana, United States
University of British Columbia
🇨🇦Vancouver, British Columbia, Canada
Central Sooner Research
🇺🇸Norman, Oklahoma, United States
XLR8 Medical Research
🇨🇦Windsor, Ontario, Canada
Clinical Research Solutions - Jackson
🇺🇸Jackson, Tennessee, United States
The Skin Centre
🇦🇺Benowa, Queensland, Australia
Skin and Cancer Foundation
🇦🇺Carlton, Victoria, Australia
Synexus Magyarorszag
🇭🇺Budapest, Hungary
Interspond - Savin Medical Group
🇺🇸Miami Lakes, Florida, United States
Indago Research and Health Center
🇺🇸Hialeah, Florida, United States
Johnson Dermatology
🇺🇸Fort Smith, Arkansas, United States
New England Research Associates
🇺🇸Bridgeport, Connecticut, United States
Debreceni Egyetem Klinikai Kozpont
🇭🇺Debrecen, Hungary
Pecsi Tudomanyegyetem Klinikai Kozpont
🇭🇺Pecs, Hungary
Local Institution - 0237
🇮🇱Haifa, Israel
Local Institution - 0067
🇯🇵Osaka, Japan
Local Institution - 0305
🇰🇷Seoul, Korea, Republic of
Local Institution - 0245
🇦🇺Box Hill, Victoria, Australia
Local Institution - 0090
🇨🇦London, Ontario, Canada
Synexus Magyarorszag Egeszsegugyi Szolgaltato - Gyula
🇭🇺Gyula, Hungary
Kobe University Hospital
🇯🇵Kobe, Hyogo, Japan
Jichi Medical University Hospital
🇯🇵Shimotsuke, Tochigi, Japan
Local Institution - 0104
🇵🇱Bialystok, Poland
Local Institution - 0234
🇺🇸Methuen, Massachusetts, United States
Northwest Arkansas Clinical Trials Center, PLLC
🇺🇸Rogers, Arkansas, United States
Semmelweis Egyetem
🇭🇺Budapest, Hungary
Clinical Research Consortium - Las Vegas
🇺🇸Las Vegas, Nevada, United States
Local Institution - 0037
🇺🇸Greer, South Carolina, United States
Tokai University Hospital
🇯🇵Isehara City, Kanagawa, Japan
Local Institution - 0062
🇯🇵Shinagawa, Tokyo, Japan
Local Institution - 0054
🇰🇷Busan, Korea, Republic of
ClinicMed Daniluk Nowak Spolka Jawna
🇵🇱Bialystok, Poland
High-Med Przychodnia Specjalistyczna
🇵🇱Warszawa, Poland
Rivergate Dermatology - Main Office
🇺🇸Goodlettsville, Tennessee, United States
Coastal Carolina Research Center - Mount Pleasant
🇺🇸North Charleston, South Carolina, United States
Lynderm Research
🇨🇦Markham, Ontario, Canada
Local Institution - 0258
🇨🇦Quebec, Canada
Praxis Dr. med. Wilfried Steinborn
🇩🇪Straubing, Germany
Allergo-Derm Bakos
🇭🇺Szolnok, Hungary
Local Institution - 0076
🇯🇵Nankoku, Kochi, Japan
Kurashiki Central Hospital
🇯🇵Kurashiki, Okayama, Japan
Centrum Kliniczno Badawcze J Brzezicki B Gornikiewicz Brzezicka Lekarze Spolka Partnerska
🇵🇱Elblag, Poland
Pratia MCM Krakow
🇵🇱Krak, Poland
Japan Community Health Care Organization Tokyo Yamate Medical Center
🇯🇵Shinjuku-ku, Tokyo, Japan
Teikyo University Hospital
🇯🇵Itabashi-Ku, Tokyo, Japan
Nihon University Itabashi Hospital
🇯🇵Itabashi-ku, Tokyo, Japan
Local Institution - 0292
🇨🇳Shanghai, Shanghai, China
Tokyo Medical University Hospital
🇯🇵Shinjuku-ku, Tokyo, Japan
The Jikei University Hospital
🇯🇵Minato-ku, Tokyo, Japan
ZDROWIE OSTEO-MEDIC s.c. Lidia i Artur Racewicz, Agnieszka i Jerzy Supronik
🇵🇱Bialystok, Poland
Local Institution - 0125
🇵🇱Torun, Poland
Local Institution - 0222
🇷🇺Yaroslavl, Russian Federation
Local Institution - 0111
🇵🇱Warsaw, Poland
ETG - Warszawa
🇵🇱Warszawa, Poland
Centrum Medyczne Oporow
🇵🇱Wroclaw, Poland
Local Institution - 0187
🇷🇺Krasnodar, Russian Federation
Local Institution - 0169
🇷🇺Moscow, Russian Federation
Local Institution - 0289
🇵🇷San Juan, Puerto Rico
Local Institution - 0182
🇷🇺Saint Petersburg, Russian Federation
Sinclair Dermatology
🇦🇺East Melbourne, Victoria, Australia
Synexus - Orange Grove Family Practice
🇺🇸Tucson, Arizona, United States
Wiseman Dermatology Research
🇨🇦Winnipeg, Manitoba, Canada
Local Institution - 0170
🇺🇸Boca Raton, Florida, United States
Burke Pharmaceutical Research
🇺🇸Hot Springs, Arkansas, United States
Local Institution - 0206
🇺🇸Fresno, California, United States
Interspond - Long Beach Clinical Trials
🇺🇸Long Beach, California, United States
Local Institution - 0236
🇺🇸Los Angeles, California, United States
Dermatology Research Associates - Los Angeles
🇺🇸Los Angeles, California, United States
Therapeutics Clinical Research
🇺🇸San Diego, California, United States
NorthBay Clinical Research
🇺🇸Santa Rosa, California, United States
Clinical Science Institute
🇺🇸Santa Monica, California, United States
Local Institution - 0094
🇺🇸San Luis Obispo, California, United States
Synexus - Santa Rosa
🇺🇸Santa Rosa, California, United States
Local Institution - 0042
🇺🇸Sherman Oaks, California, United States
Care Access Research - Walnut Creek
🇺🇸Walnut Creek, California, United States
ERN - Accel Research Sites
🇺🇸DeLand, Florida, United States
Stamford Therapeutics Consortium
🇺🇸Stamford, Connecticut, United States
LCC Medical Research
🇺🇸Miami, Florida, United States
Local Institution - 0198
🇺🇸Port Orange, Florida, United States
Local Institution - 0013
🇺🇸Marietta, Georgia, United States
Local Institution - 0235
🇺🇸Sandy Springs, Georgia, United States
Dundee Dermatology
🇺🇸West Dundee, Illinois, United States
Springfield Clinic
🇺🇸Springfield, Illinois, United States
Deaconess Clinic Downtown
🇺🇸Evansville, Indiana, United States
Local Institution - 0020
🇺🇸Plainfield, Indiana, United States
Clinical Research Advantage - Evansville - South Kenmore Drive
🇺🇸Evansville, Indiana, United States
The South Bend Clinic
🇺🇸South Bend, Indiana, United States
Shondra L. Smith, M.D.
🇺🇸Lake Charles, Louisiana, United States
DermCare Experts
🇺🇸Quincy, Massachusetts, United States
Local Institution - 0025
🇺🇸Troy, Michigan, United States
Hamzavi Dermatology
🇺🇸Fort Gratiot, Michigan, United States
Washington University School of Medicine - West County Dermatology
🇺🇸Saint Louis, Missouri, United States
Hassman Research Institute
🇺🇸Berlin, New Jersey, United States
Local Institution - 0016
🇺🇸East Windsor, New Jersey, United States
Local Institution - 0058
🇺🇸New York, New York, United States
Forest Hills Dermatology Group
🇺🇸Kew Gardens, New York, United States
Local Institution - 0218
🇺🇸Stony Brook, New York, United States
PMG Research of Cary
🇺🇸Cary, North Carolina, United States
ClinOhio Research Services
🇺🇸Columbus, Ohio, United States
Local Institution - 0176
🇺🇸Fairborn, Ohio, United States
Wilmington Dermatology Center
🇺🇸Wilmington, North Carolina, United States
Local Institution - 0045
🇺🇸Exton, Pennsylvania, United States
Local Institution - 0004
🇺🇸Rapid City, South Dakota, United States
Bellaire Dermatology
🇺🇸Bellaire, Texas, United States
Local Institution - 0195
🇺🇸Dallas, Texas, United States
Local Institution - 0006
🇺🇸Arlington, Texas, United States
Local Institution - 0030
🇺🇸Dallas, Texas, United States
University of Texas Health Science Center at San Antonio
🇺🇸San Antonio, Texas, United States
Austin Institute for Clinical Research - Pflugerville
🇺🇸Pflugerville, Texas, United States
Center for Clinical Studies - Webster
🇺🇸Webster, Texas, United States
Interspond - Acclaim Dermatology
🇺🇸Sugar Land, Texas, United States
Woden Dermatology
🇦🇺Phillip, Australian Capital Territory, Australia
Local Institution - 0265
🇺🇸Seattle, Washington, United States
St. George Dermatology & Skin Care Centre
🇦🇺Kogarah, New South Wales, Australia
Holdsworth House Medical Practice
🇦🇺Darlinghurst, New South Wales, Australia
Local Institution - 0250
🇦🇺Westmead, New South Wales, Australia
North Eastern Health Specialists
🇦🇺Hectorville, South Australia, Australia
Veracity Clinical Research
🇦🇺Woolloongabba, Queensland, Australia
Local Institution - 0251
🇦🇺Parkville, Victoria, Australia
Beacon Dermatology
🇨🇦Calgary, Alberta, Canada
Stratica Medical
🇨🇦Edmonton, Alberta, Canada
CCA Medical Research
🇨🇦Ajax, Ontario, Canada
SkinFit MD Laser and Cosmetic Clinic
🇨🇦Surrey, British Columbia, Canada
Mediprobe Research
🇨🇦London, Ontario, Canada
DermEdge
🇨🇦Mississauga, Ontario, Canada
North Bay Dermatology Centre
🇨🇦North Bay, Ontario, Canada
Local Institution - 0088
🇨🇦Peterborough, Ontario, Canada
Office of Dr. Niakosari Firouzeh
🇨🇦North York, Ontario, Canada
Institute of Cosmetic and Laser Surgery
🇨🇦Oakville, Ontario, Canada
Local Institution - 0082
🇨🇦Richmond Hill, Ontario, Canada
Local Institution - 0132
🇨🇦Toronto, Ontario, Canada
Toronto Dermatology Centre
🇨🇦Toronto, Ontario, Canada
Kim Papp Clinical Research
🇨🇦Waterloo, Ontario, Canada
Docteur David Gratton Dermatologue
🇨🇦Montreal, Quebec, Canada
Siena Medical Research
🇨🇦Montreal, Quebec, Canada
Local Institution
🇨🇳Taipei, Taiwan
Nemocnice Jihlava
🇨🇿Jihlava 1, Czechia
Local Institution - 0312
🇨🇳Nanjing, Jiangsu, China
Nemocnice Novy Jicin a.s.
🇨🇿Novy Jicin, Czechia
Local Institution - 0279
🇫🇮Tampere, Finland
Sanatorium profesora Arenbergera
🇨🇿Praha 1, Czechia
MUDr. Helena Korandova
🇨🇿Olomouc, Czechia
Fakultni Nemocnice Ostrava
🇨🇿Ostrava, Czechia
Clintrial
🇨🇿Praha 10, Czechia
Krajska zdravotni - Masarykova nemocnice v Usti nad Labem
🇨🇿Usti nad Labem, Czechia
Centre Hospitalier Universitaire de Nice Hopital lArchet
🇫🇷Nice cedex 3, France
Licca Clinical Research Institute
🇩🇪Augsburg, Germany
Hautarztpraxis Dr. Beatrice Gerlach
🇩🇪Dresden, Germany
Synexus Frankfurt Clinical Research
🇩🇪Frankfurt am Main, Germany
Local Institution - 0263
🇩🇪Hamburg, Germany
Dermakiel - Allergie Und Haut Centrum
🇩🇪Kiel, Germany
Praxis Dr. Beate Schwarz
🇩🇪Langenau, Germany
Hautarztpraxis Dr. Niesmann & Dr. Othlinghaus
🇩🇪Bochum, Germany
CentroDerm Privatklinik
🇩🇪Wuppertal, Germany
Qualiclinic Egeszsegugyi Szolgaltato es Kutatasszervezo Kft.
🇭🇺Budapest, Hungary
Synexus Magyarorszag Egeszsegugyi Szolgaltato - Debrecen Affiliated Site
🇭🇺Debrecen, Hungary
Josa Andras Oktatokorhaza - Szabolcs Szatmar-Bereg Megyei Onkormanyzat
🇭🇺Nyiregyhaza, Hungary
Synexus Magyarorszag Egeszsegugyi Szolgaltato - Zalaegerszeg
🇭🇺Zalaegerszeg, Hungary
Local Institution - 0065
🇯🇵Nagoya, Aichi, Japan
Fukuoka University Hospital
🇯🇵Fukuoka-shi, Fukuoka, Japan
Sapporo Skin Clinic
🇯🇵Sapporo, Hokkaido, Japan
Local Institution - 0075
🇯🇵Yokohama-Shi, Kanagawa, Japan
Yokohama City University Hospital
🇯🇵Yokohama, Kanagawa, Japan
Kyoto University Hospital
🇯🇵Kyoto-City, Kyoto, Japan
Local Institution - 0066
🇯🇵Kyoto-city, Kyoto, Japan
Mie University Hospital
🇯🇵Tsu, MIE, Japan
Local Institution - 0072
🇯🇵Matsumoto, Nagano, Japan
Hamamatsu University Hospital
🇯🇵Hamamatsu, Shizuoka, Japan
Kumamoto University Hospital
🇯🇵Kumamoto, Japan
Local Institution - 0073
🇯🇵Osaka, Japan
Local Institution - 0310
🇰🇷Gwangju, Korea, Republic of
Local Institution - 0053
🇰🇷Seoul, Korea, Republic of
Local Institution - 0138
🇵🇱Warszawa, MZ, Poland
Synexus Polska Oddzial w Gdyni
🇵🇱Gdynia, Poland
Zespol Naukowo-Leczniczy Iwolang
🇵🇱Iwonicz-Zdroj, Poland
Synexus - Katowice
🇵🇱Katowice, Poland
Centrum Terapii Wspolczesnej
🇵🇱Lodz, Poland
Local Institution - 0144
🇵🇱Lodz, Poland
Centrum Medyczne All-Med
🇵🇱Lodz, Poland
Local Institution - 0114
🇵🇱Lodz, Poland
Miejski Szpital Zespolony w Olsztynie
🇵🇱Olsztyn, Poland
Niepubliczny Zaklad Opieki Zdrowotnej MED-LASER
🇵🇱Lublin, Poland
DermoDent - Centrum Medyczne Czajkowscy
🇵🇱Osielsko, Poland
Local Institution - 0103
🇵🇱Poznan, Poland
ETG - Siedlce
🇵🇱Siedlce, Poland
ETG - Skierniewice
🇵🇱Skierniewice, Poland
Clinical Research Group
🇵🇱Warszawa, Poland
dermMedica Sp. z o.o.
🇵🇱Wroclaw, Poland
Local Institution - 0178
🇷🇺Ekaterinburg, Russian Federation
Local Institution - 0137
🇵🇱Wroc?aw, Poland
Local Institution - 0124
🇵🇱Wroclaw, Poland
Local Institution - 0172
🇷🇺Kazan, Russian Federation
Local Institution - 0171
🇷🇺Moscow, Russian Federation
Local Institution - 0175
🇷🇺Moscow, Russian Federation
Local Institution - 0201
🇷🇺Saint Petersburg, Russian Federation
Local Institution - 0190
🇷🇺Ryazan, Russian Federation
Local Institution - 0179
🇷🇺Saint Petersburg, Russian Federation
Local Institution - 0202
🇷🇺Saratov, Russian Federation
Local Institution - 0223
🇪🇸Alcorcon, Spain
Hospital Universitari Germans Trias i Pujol
🇪🇸Badalona, Spain
Local Institution - 0225
🇪🇸Cordoba, Spain
Local Institution - 0226
🇪🇸Las Palmas De Gran Canaria, Spain
ProbarE i Lund
🇸🇪Lund, Sweden
Hospital de Manises
🇪🇸Manises, Spain
Hospital Universitario Quironsalud Madrid
🇪🇸Pozuelo de Alarcon, Spain
Ladulaas Kliniska Studier
🇸🇪Boras, Sweden
Local Institution - 0186
🇸🇪Solna, Sweden
Local Institution - 0153
🇨🇳Taipei, Taiwan
Local Institution - 0079
🇨🇳Kaohsiung, Taiwan
Local Institution - 0297
🇨🇳Kaohsiung, Taiwan
MAC Clinical Research - Cannock
🇬🇧Cannock, United Kingdom
Synexus - Manchester Clinical Research Centre
🇬🇧Chorley, United Kingdom
Burbage Surgery
🇬🇧Leicestershire, United Kingdom
Synexus - Merseyside Clinical Research Centre
🇬🇧Chorley, United Kingdom
Mounts Bay Medical
🇬🇧Cornwall, United Kingdom
MAC Clinical Research - Stockton
🇬🇧Durham, United Kingdom
Salford Royal NHS Foundation Trust
🇬🇧Manchester, United Kingdom
The Dudley Group NHS Foundation Trust
🇬🇧Dudley, United Kingdom
Guys and Saint Thomas NHS Foundation Trust
🇬🇧London, United Kingdom
MAC Clinical Research - Manchester
🇬🇧Manchester, United Kingdom
MAC Clinical Research - Liverpool
🇬🇧Prescot, United Kingdom
Total Skin and Beauty Dermatology Center
🇺🇸Birmingham, Alabama, United States
Local Institution - 0278
🇺🇸Birmingham, Alabama, United States
Local Institution - 0233
🇺🇸Tampa, Florida, United States
Local Institution - 0008
🇺🇸Tampa, Florida, United States
Local Institution - 0040
🇺🇸Louisville, Kentucky, United States
David Fivenson MD Dermatology
🇺🇸Ann Arbor, Michigan, United States
Unity Clinical Research
🇺🇸Oklahoma City, Oklahoma, United States
Local Institution - 0009
🇺🇸Portland, Oregon, United States
Local Institution - 0167
🇺🇸Portland, Oregon, United States
Clinical Research Center of the Carolinas
🇺🇸Charleston, South Carolina, United States
Ora
🇺🇸Chestnut Hill, Massachusetts, United States
Local Institution - 0017
🇺🇸Irvine, California, United States
Dermatology Associates of Knoxville
🇺🇸Knoxville, Tennessee, United States
The Skin Wellness Center
🇺🇸Knoxville, Tennessee, United States
Local Institution - 0055
🇰🇷Seoul, Korea, Republic of
Hospital Universitario Ramon Y Cajal
🇪🇸Madrid, Spain
Montefiore Medical Center - Bronx
🇺🇸Bronx, New York, United States
Treasure Valley Dermatology & Skin Cancer Center
🇺🇸Meridian, Idaho, United States
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