Treatment monitoring using FDG-PET/CT and FLT-PET/CT in patients with Hodgkin Lymphoma. - PET/CT treatment monitoring in Hodgkin Lymphoma.

Phase 1

• Conditions: Hodgkin Lymphoma

• Registration Number: EUCTR2009-017587-16-GB
• Lead Sponsor: Barts Health NHS Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-11-04
• Study Completion: 2012-09-07
• Last Update Posted: 28 February 2019

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Males and Females; aged > 18 years (no upper limit) 2.Histological diagnosis of Hodgkin Lymphoma(HL) according to WHO lymphoma classification. 3.Receiving ChlVPP chemotherapy. 4.Performance status (ECOG) 0-2. 5.Able and willing to give written informed consent and to comply with the study protocol procedures
Are the trial subjects under 18? no
Number of subjects for this age range: 0
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 0
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 0

Exclusion Criteria

1.Primary Central Nervous System (CNS) lymphoma. 2.Contraindication to any of the drugs contained in the chemotherapy regimen. 3.Previous or concurrent malignant disease unless basal or squamous cell carcinoma of the skin or in situ carcinoma of the cervix or the patient has been disease-free for more than 2 years. 4.Any other serious active disease that in the opinion of the investigator might preclude the patient from having conventional chemotherapy. 5.Females of child bearing potential must have a negative pregnancy test prior to starting the study. Females must not be pregnant or lactating Females of child bearing potential and all males must be willing to use an effective method of contraception (hormonal or barrier method of birth control; abstinence) for the duration of the study and for up to 3 months after the last FDG-PET/CT and FLT-PET/CT scans. Note: subjects are not considered of childbearing potential if they are surgically sterile (they have undergone a hysterectomy, bilateral tubal ligation or bilateral oophorectomy) or they are postmenopausal 6.Medical or psychiatric illness, which makes the patient unsuitable or unable to give informed consent.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified