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临床试验/NCT00225459
NCT00225459已完成不适用

Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.

University of Saskatchewan1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2005年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
1

研究概览

简要总结

The purpose of this study is to determine whether or not spiritual and/or religious commitment affects mood variability and thoughts of suicide.

First we hypothesize that among patients with depressive symptoms, those who have higher religious/spiritual (R/S) commitment will have less suicidal ideation and less mood variability. Second, we hypothesize that higher mood variability will be associated with more suicidal ideation. Finally, dependent on the first two hypotheses, we propose that R/S commitment will mediate the relationship between mood variability and suicidal ideation.

详细描述

The suicide rate has not changed dramatically in the recent past, despite advances in psychiatric and mental health treatment, suicide prevention and awareness programs, and reorganization of health services. Depression and the mood disorders which may affect 15% of the population are the conditions most associated with high suicide rates (in addition to psychotic conditions that are relatively rare). Research findings into specific conditions within the depressive disorders that might predict suicidal tendencies are sparse, except for other common comorbid conditions such as panic and alcohol abuse. Research into risks and protective factors has infrequently included religious and spiritual variables that have been associated with decreased rates of depression, suicide, suicide attempts and suicidal ideation.

An inverse relationship between religion and suicide has been found in regional, national, and cross-national studies. Analyzing data from the 1993 Mortality Followback Survey in the US, frequency of religious activities reduced the odds of dying by suicide even after controlling for the frequency of social contact; in 584 deaths by suicide compared with 4279 natural deaths. A Canadian study of 261 Census divisions found the absence of religious affiliation to be an important predictor of death by suicide.

There are no known studies examining mood variability and religion, or spirituality directly. A number of studies however have examined personality attributes and religiosity. The personality style of neuroticism includes moodiness and negative emotionality with the concept of mood reactivity being germane to its construct. Neuroticism is highly correlated with depression and may be a higher order factor in the "internalizing disorders" which include the depressive and anxiety disorders.

The objective of this study is to answer the question "Does R/S mediate the relationship between mood variability and suicidal ideation?" In an effort to achieve that objective, there are three questions that must be answered in this population which in themselves are significant contributions to the research literature.

  1. Is there an association between mood variability and suicidal ideation?
  2. Is there an association between mood variability and religion?
  3. Is there an association between religion and suicidal ideation?

研究设计

研究类型
Observational
观察模型
Case Crossover
时间视角
Prospective

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Inpatients and outpatients.
  • DSM-IV defined major depression.
  • Comorbid anxiety, bipolar spectrum, and schizoaffective (depressive type).
  • Males and females between the ages of 18 and 70.

排除标准

  • Involuntary patients.
  • In/out patients with current psychosis.
  • In/out patients with neurological impairment.
  • In/out patients with current substance dependence.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Marilyn Baetz

Professor of Psychiatry

University of Saskatchewan

研究点 (1)

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