A study to evaluate the role of acid suppression medication in reducing post banding ulcers and re bleeding after ligation of bleeding oesophageal varices (dilated blood vessels) in patients with liver cirrhosis
Not Applicable
- Conditions
- Health Condition 1: K740- Hepatic fibrosis
- Registration Number
- CTRI/2023/06/054442
- Lead Sponsor
- Post Graduate Institute of Medical Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Diagnosed cases of liver cirrhosis presenting with decompensation in the form of first episode of variceal bleed
Exclusion Criteria
1-Refractory bleed requiring TIPSS or emergency surgery apart from EVL
2-Upper GI bleed due to acid peptic disease/GERD
3-Hepatocellular carcinoma
4-upper GI Bleed due to malignant tutors go the GI tract
5-Hemodynamic instability requiring vasopressor support
6-Hepatic encephalopathy grade III or above
7-History of surgery of oesophagus, stomach or liver
8- Renal failure with creatinine >2mg/dl
9-Presence of gastric varices as source of upper GI bleed
10-Pregnancy/breastfeeding
11-PPI allergy
12-Mising informed consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method