Hyaluronan in Embryo Transfer Media

Completed

• Conditions: Infertility

• Registration Number: NCT02077608
• Lead Sponsor: Peter Fancsovits, Ph.D.

Brief Summary

Prospective randomized double blind comparison of hyaluronan enriched embryotransfer media and conventional embryotransfer media in human IVF treatments. Embryos selected for transfer are incubated in a culture media containing high concentration of hyaluronan or low concentration of hyaluronan.

Primary outcome: implantation and pregnancy rates

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Primary Completion: 2012-08
• Study Completion: 2013-12
• Study First Submitted: 2014-02-28
• Status Verified: 2014-03
• Study First Submitted QC: 2014-03-03
• Last Update Submitted: 2014-03-03
• Study First Posted: 2014-03-04
• Last Update Posted: 2014-03-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 580

Inclusion Criteria

• Infertile patients
• entering in vitro fertilization treatment
• at least 1 embryo transferred

Exclusion Criteria

• IVF treatment with donated oocytes
• No embryo available for transfer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rate	5 weeks after embryo transfer	Number of clinical pregnancies (gestational sacs visible by ultrasound examination) divided by the number of embryotransfers
Implantation rate	5 weeks after embryotransfer	Number of embryos implanted (No. of gestational sacs) divided by the number of embryos implanted

Secondary Outcome Measures

Name	Time	Method
Multiple pregnancy rate	5 weeks after embryotransfer	Number of multiple pregnancies divided by the number of embryotransfers
Delivery rate	40 weeks after embryo transfer	Number of delivery divided by the number of embryo transfers

Trial Locations

Locations (1)

Semmelweis University First Department of Obstetrics and Gynecology; 🇭🇺 Budapest, Hungary