Safety of Cardioversion of Acute Atrial Fibrillation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 7,700
- 试验地点
- 3
- 主要终点
- Incidence and predictors of thromboembolic complications, especially stroke, and death <31 days after cardioversion of acute AF
研究概览
简要总结
The purpose of this study is to investigate the complications of cardioversion of acute (<48 hours duration) atrial fibrillation (AF).
Primary Outcome Measures:
- Incidence and predictors of thromboembolic complications, especially stroke, and death <31 days after cardioversion of acute AF
Secondary Outcome Measures:
- Number of therapy non-responder and early recurrence of AF
- Bleeding complications during the 31 days follow-up
- Hemodynamic complications of cardioversion
Estimated Enrollment: 3000 cases
Study Start Date: Jun 2011
Estimated Study Completion Date: December 2011
详细描述
It has been a common practice to perform cardioversion of acute (<48 hour) AF without any anticoagulation. The new European guidelines recommend that anticoagulation should be started already before cardioversion in all patients with CHADS2VASC score indicating need for long-term oral anticoagulation. The evidence behind these guidelines is, however, scarce. In this retrospective study we collect data on the safety of acute AF cardioversion from emergency rooms of two university hospitals and one secondary referral center from the years 2003-2010.
Inclusion criteria:
All patients admitted to emergency room because of acute AF in whom electrical or pharmacological cardioversion was attempted <48 from the beginning of the symptoms.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients admitted to emergency room because of acute AF in whom electrical or pharmacological cardioversion was attempted <48 from the beginning of the symptoms
排除标准
- •duration of the AF is unknown or >48 hours
结局指标
主要结局
Incidence and predictors of thromboembolic complications, especially stroke, and death <31 days after cardioversion of acute AF
时间窗: 31 days
次要结局
- Bleeding complications during the 31 days follow-up(31 days)
- Hemodynamic complications of cardioversion(31 days)
- Number of therapy non-responder and early recurrence of AF(31 days)
研究者
Juhani Airaksinen
Professor
Turku University Hospital