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Iron and Vitamin Supplementation in Hip/Knee Surgery

Not Applicable
Completed
Conditions
Anemia
Iron Poor Blood
Orthopedic Disorder
Hip Arthropathy
Knee Arthropathy
Interventions
Dietary Supplement: Iron plus folic acid, vitamin B2, B6, B12, C, and E
Registration Number
NCT04880499
Lead Sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Brief Summary

Randomized controlled trial to evaluate the efficacy of oral iron supplementation plus cofactors in reducing the prevalence of preoperative anemia in a cohort of 60 patients undergoing elective prosthetic hip or knee surgery.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Males and females
  • ASA 1, 2, or 3
  • No neuropsychiatric conditions
  • Acceptance of informed consent
  • Elective prosthetic hip or knee surgery
Exclusion Criteria
  • ASA 4
  • Present or past neuropsychiatric conditions
  • Hip or knee revision surgery
  • Use of iron as dietary supplement
  • Known erythrocytosis
  • Incompatible hypersensitivities
  • Iron metabolism disorders
  • Lymphoproliferative disorders

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Intervention (group A)Iron plus folic acid, vitamin B2, B6, B12, C, and EPatients who are subjected to the intervention, being iron plus other cofactors for hematopoiesis, other than the standard of care.
Primary Outcome Measures
NameTimeMethod
Change of blood hemoglobin levelsBaseline and 60 days +/- 15 days

Change of hemoglobin concentration (g/dl) from baseline and after 60 days +/- 15 days

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Istituto Ortopedico Galeazzi

🇮🇹

Milan, Italy

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