Effect Yoga in Addition to TENS on Diabetic Glaucoma
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Intraoccular pressure measurement
研究概览
简要总结
Intraocular pressure (IOP) is maintained by a balance between aqueous production and outflow with an imbalance leading to elevated eye pressure. Very high levels of IOP will subject retinal cells to mechanical stress. In addition to mechanical injury, IOP elevation can impair ocular blood flow reducing perfusion pressure to retinal neurons. Long-term vascular and mechanical stresses can produce further injury at the optic nerve.
Elevated intraocular pressure (IOP) or ocular hypertension (OHT) is the only well-established modifiable risk factor for primary open-angle glaucoma (POAG), the most common form of glaucoma. Glaucoma is a class of optic neuropathy. It is main leading cause of blindness.
Glaucoma is classified on the basis of anatomic features as open angle (where the anterior chamber angle of the eye remains open) and angle-closure (with closure of the anterior chamber angle). Glaucoma is considered primary if the eye has no preexisting disease. Secondary forms of glaucoma are caused by various ocular or systemic diseases such as pigment dispersion syndrome and ocular trauma.
It seems reasonable to consider that a longer duration of diabetes mellitus (DM) with a prolonged insult to the retina and optic nerve via vascular, glial, and neuronal factors would be associated with a higher risk of OAG.
详细描述
patients with diabetic glaucoma (80 patients ) from both sexes will be divided to 2 groups, 40 patients for each group;
study group will receive only one session of 20 minutes yoga ocular training for 20 minutes followed by transcutaneous electrical nerve stimulation (TENS) by placing electrodes on skin over urinary bladder (BL) acupoints 61 and 62 for 20 minutes
control group will be treated with the same protocol as the study group but with the TENS unit is off.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with DM duration more than 5 years .
- •BMI will be < 30 kg/m² .
- •patients with bilateral primary open-angle glaucoma.
排除标准
- •acute or chronic eye inflammation
- •eye surgeries
- •mental ill patients
- •patients who will refuse to participate in the study
研究组 & 干预措施
study group
study group will receive only one session of yoga eye exercise for 20 minutes followed by transcutaneous electrical nerve stimulation by placing electrodes on skin over urinary bladder (BL) acupoints 61 and 62 for 20 minutes
干预措施: active TENS (Device)
control group
control group will be treated with the same protocol as the study group but with the unit of transcutaneous electrical nerve stimulation is off .
干预措施: sham TENS (Device)
结局指标
主要结局
Intraoccular pressure measurement
时间窗: immediately after the session
it will be measured in right and left eye
次要结局
- Intraoccular pressure measurement(immediately after sixty minutes of session end)
- Intraoccular pressure measurement(immediately after thirty minutes of session)
研究者
Ali Mohamed Ali ismail
lecturer of Physical Therapy for Cardiovascular / Respiratory Disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Cairo University
