Effect of Mitomycin C on Urethral Stricture Recurrence After Internal Urethrotomy

Phase 1

• Conditions: Urethral Stricture
• Interventions: Procedure: Internal urethrotomy; Drug: Mitomycin C - local injection

• Registration Number: NCT00918528
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The aim of this study is to evaluate the efficacy of local injected mitomycin C at the time of internal urethrotomy in order to prevent the recurrence of urethral strictures.

Detailed Description

Not available

Study Timeline

• Status Verified: 2009-06
• Study Start: 2009-06
• Study First Submitted: 2009-06-09
• Study First Submitted QC: 2009-06-10
• Last Update Submitted: 2009-06-10
• Study First Posted: 2009-06-11
• Last Update Posted: 2009-06-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

• Male urethral stricture suitable for internal urethrotomy
• Stricture length less than 10 mm

Exclusion Criteria

• Stricture length over 10 mm
• Benign prostate enlargement

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
2. Internal urethrotomy + mitomycin C	Internal urethrotomy	-
2. Internal urethrotomy + mitomycin C	Mitomycin C - local injection	-
1. Internal urethrotomy	Internal urethrotomy	-

Primary Outcome Measures

Name	Time	Method
Urethral stricture recurrence	One year

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel