Mytomycin intravesical instillation soon after nephroureterectomy

Phase 3

• Conditions: Renal pelvic cancer, ureteral cancer; Upper urinary tract carcinoma

• Registration Number: JPRN-jRCTs011180027
• Lead Sponsor: Hori Jun-ichi

Brief Summary

MMC intravesical instillation soon after doing radical nephrectomy was safe. Bladder recurrence in each condition was 25% in Ta, 67% in T1, and 100% in T3 as mentioned in other reported cases. According to the bladder cancer guideline, bladder recurrence in upper tract urothelial carcinoma was reported to be 15-50%. In conclusion, we believe that MMC intravesical instillation soon after radical nephrectomy has the potential to reduce bladder recurrence in patients with upper tract urothelial carcinoma.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-25
• Study Completion: 2020-10-15
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

patients without history of bladder cancer

Exclusion Criteria

patients with previous history of bladder cancer

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bladder recurrence

Secondary Outcome Measures

Name	Time	Method
Cancer stage, time until renal artery clumping