Effects of Non-invasive Transcranial direct current stimulation on posturographical and neurophysiological parameters in healthy and stroke.

Phase 2

Completed

Conditions: Stroke
10007963

Registration Number: NL-OMON42313

Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 25

Inclusion Criteria

Patients: A first ever lesion in the territory of the MCA as verified by CT of MRI scan more than 6 months ago.

Exclusion Criteria

Both groups: 1) Any metallic implants (pacemaker etc.) , 2) orthopedic limitations that interfere with the study 3) Cranial bone defects, 4) history of epileptic seizures, 5) insufficient cognitive function (Mini Mental State Examination, MMSE < 19).;Healthy subjects: History of any disease condition or event that interferes with the study

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Stabilogram difussion analysis of the centre of pressure.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Posturographical measurements:<br /><br>Sway amplitude and velocity.<br /><br>Weight distribution between both legs.<br /><br>The instantaneous relative phase and the associated circular variance between<br /><br>target and COP during the tracking task.<br /><br><br /><br>Neurophysiological measurements:<br /><br>Time-frequency and amplitude analysis of EEG in relevant frequency bands.<br /><br>Source localization using anatomical MRIs and beamforming methods.<br /><br><br /><br>Clinical/behavioural measurements:<br /><br>Berg balance scale (BBS).<br /><br>Functional Reach Test (FRT).<br /><br>Falls Efficacy Scale (FES).<br /><br>Timed up and Go (TUG).<br /><br>Fall history.<br /><br>Erasmus modifications to the Nottingham Sensory Assessment (EmNSA).<br /><br><br /><br>Clinical/behavioural measurements only for patients:<br /><br>Fugl-Meyer Motor Score lower extremity.<br /><br>Motricity Index (MI).<br /><br>Nothingham extended adl (NEADL).<br /><br>O-letter cancelation task (LCT)</p><br>