The effect of transcranial direct current stimulation and olfactory stimulation in intensive care unit (ICU) patients with disorder of consciousness (DOC)

Phase 3

• Conditions: Disorder of consciousness.; Altered mental status, unspecified; R41.82

• Registration Number: IRCT20240608062040N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 June 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Age above 18 years
People with brain damage
Non-hemorrhagic cerebrovascular accident (CVA)
Glasgow Coma Scale (GCS) greater than 9
No administration of neuromuscular system blockers or sedatives within 24 hours after entering the study
Diagnosis of unresponsive wakefulness syndrome (UWS) or minimally conscious state (MCS), based on repeated behavioral assessments using the Coma Recovery Scale-Revised (CRS-R) (ie, at least five assessments per week)
Patients without tracheostomy
Patients without intracerebral hemorrhage (ICH)
Patients without subarachnoid hemorrhage (SAH)
Patients without intubation
Patients without previous history of neurological or psychiatric disease
Patients who did not use neuromuscular blocking drugs or sedative drugs in the 24 hours before the test.
Patients with no documented history of previous coma, critical illness, or unstable medical condition
Patients with no history of seizures

Exclusion Criteria

The patient suffers from a complication that reduces brain function

Study & Design

• Study Type: interventional
• Study Design: Not specified