JPRN-UMIN000005853
Recruiting
未知
Randomized Phase 2 Trial of Inhaled Furosemide on the dyspnea associated with Cancer - Randomized Phase 2 Trial of Inhaled Furosemide on the dyspnea associated with Cancer
ConditionsDyspnea associated with Cancer
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Dyspnea associated with Cancer
- Sponsor
- Chiba University Hospital
- Enrollment
- 60
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- •I. The first stage 1\) Hypersensitivity reactions to furosemide, opioids and sulfonamide derivatives 2\) Severe heart failure, respiratory disease with unstable dyspnea 3\) Neurological, mental impairment with the difficulty of collecting data 4\) Drug abuse, drug dependence 5\) Pregnancy, lactation II. The second stage 1\) Inability to take oral rapid onset morphine 2\) Pain score above 3 3\) Severe hypertention(SBP \>\= 180mmHg or DBP \>\= 110mmHg) 4\) Liver failure, renal failure AST(GOT) \>\= 100IU/L ALT(GPT) \>\= 100IU/L T.bil \>\= 2\.0mg/dL eGFR \<\= 30 mL/hr 5\) Severe respiratory failure or the administration of oxygen with flow rate of 10L/min or more 6\) Ineligible condition for study in physician's judge 7\) The change in prescription of opioid, steroids and anxiolytics within 2 days prior to study 8\) The change in the chemotherapy within 7 days prior to study
Outcomes
Primary Outcomes
Not specified
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