NL-OMON33598
Completed
Not Applicable
A PET study of dopamine function in healthy subjects with hallucinations - dopamine function in healthy subjects with hallucinations
niversitair Medisch Centrum Utrecht0 sites20 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- hallucinations
- Sponsor
- niversitair Medisch Centrum Utrecht
- Enrollment
- 20
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Physically healthy subjects, evaluated by medical history, physical examination and screening laboratory tests
- •Experiences hallucinations with a frequency of at least once a week.
- •Total SPQ score lower than 25
- •No diagnosis on axis I or II based on DSM \-IV criteria, confirmed by the CASH and the SCID II interview.
- •Age between 18\-60
Exclusion Criteria
- •Use of psychotropic medication within four weeks before the scanning
- •Drug or alcohol\-abuse over a period of three weeks prior to the experiment. More then 15 cigarettes and more then 6 cups of caffeine containing coffee, cola or tea.
- •A history of neurological illness or other medical problems potentially having central nervous system sequellae.
- •Pregnancy, breast feeding and use of inadequate anti\-conception.
- •Use of other medication potentially influencing cerebral blood flow.
- •Claustrophobia
- •Exposure to radioactivity leading to yearly cumulative dose of 10 mSv or more
- •Metal objects in or around the body (braces, pacemaker, metal fragments);
- •Exposure to radioactivity leading to a yearly cumulative dose of 10 mSv or more.
Outcomes
Primary Outcomes
Not specified
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