NL-OMON33598CompletedNot Applicable
A PET study of dopamine function in healthy subjects with hallucinations - dopamine function in healthy subjects with hallucinations
niversitair Medisch Centrum Utrecht0 sites20 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 20
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •Physically healthy subjects, evaluated by medical history, physical examination and screening laboratory tests
- •Experiences hallucinations with a frequency of at least once a week.
- •Total SPQ score lower than 25
- •No diagnosis on axis I or II based on DSM -IV criteria, confirmed by the CASH and the SCID II interview.
- •Age between 18-60
Exclusion Criteria
- •Use of psychotropic medication within four weeks before the scanning
- •Drug or alcohol-abuse over a period of three weeks prior to the experiment. More then 15 cigarettes and more then 6 cups of caffeine containing coffee, cola or tea.
- •A history of neurological illness or other medical problems potentially having central nervous system sequellae.
- •Pregnancy, breast feeding and use of inadequate anti-conception.
- •Use of other medication potentially influencing cerebral blood flow.
- •Claustrophobia
- •Exposure to radioactivity leading to yearly cumulative dose of 10 mSv or more
- •Metal objects in or around the body (braces, pacemaker, metal fragments);
- •Exposure to radioactivity leading to a yearly cumulative dose of 10 mSv or more.
Investigators
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