Combined Effect of Aerobic Exercise and Mediterranean Diet on Inflammatory Markers and Quality of Life in Obese Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Short Form Quality of Life Questionnaire (SF-36)
研究概览
简要总结
All study group patients performed aerobic exercise on a treadmill. approved by the American College of Sports Medicine.
Both groups received a Mediterranean diet for 12 weeks tailored according to patients' caloric needs
详细描述
All study group patients performed aerobic exercise on a treadmill approved by the American College of Sports Medicine. The program started with a warming-up phase through walking on a treadmill for 3-5 minutes at a slow speed. Then, 10-30 minutes of aerobic exercise training with moderate intensity (60-70% of maximum heart rate) and 10 minutes of cooling down with low speed and without inclination. Participants had 3 sessions/week for 3 months with close supervision of a physical therapist.
Both groups received a Mediterranean diet for 12 weeks tailored to patients' caloric needs. They received instructions about the consumption of olive oil as added lipid, the consumption of nuts and olives as snacks, daily high consumption of vegetables, fruits, and whole grains, dairy products, bi-weekly consumption of legumes, bi-weekly consumption of fish, and monthly consumption of meat. The main beneficial components of the Mediterranean diet are monounsaturated fats such as oleic acid in olive oil, polyunsaturated fats such as omega-3, high amounts of flavonoids and antioxidants found in fruits and vegetables, and high amounts of fiber found mainly in foods with a low glycemic index
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Obese patients with BMI ranged from 30-39.9 kg/m
- •Their age was from 35 to 45 years old.
- •Both genders.
- •Stable vital signs (blood pressure, respiratory rate and temperature)
- •Abdominal obesity measurements according to American heart association)
- •Obese patients have one or more abnormal value of lipids profile.
- •All patients with sedentary life style.
- •All patients had insulin resistance
排除标准
- •Rheumatic, neurologic, cardiovascular, respiratory, renal, lung problems, malignant tumors, and undiagnosed fever, which would prevent them from participating in aerobic exercises.
- •Knee injury or knee surgery during the past six month or having a history of joint replacement or fracture or hereditary or acquired musculoskeletal disorders in lower limb.
- •Major vision disorders.
- •Drugs that would affect metabolism or balance.
- •Assistive devices for walking.
- •Pregnancy or breast feeding, and post-partum 12 months.
- •Abdominal or rectal anus surgery.
研究组 & 干预措施
study group
aerobic exercise program and Mediterranean diet
干预措施: aerobic exercise program (Other)
study group
aerobic exercise program and Mediterranean diet
干预措施: Mediterranean diet (Other)
control group
Mediterranean diet
干预措施: Mediterranean diet (Other)
结局指标
主要结局
Short Form Quality of Life Questionnaire (SF-36)
时间窗: 12 weeks
To measure the health related quality of life (HRQOL)in obese patient. SF-36 (version 2.0) is a 36-item measure of generic HRQOL in which 35 questions are transformed into eight dimensions; physical functioning, role limitation to physical problems, bodily pain, general health, vitality, social functioning, role limitations to emotional problems, and mental health Scores on all eight dimensions range from zero to 100, where higher scores represent better HRQOL
次要结局
- Laboratory Measurements(12 weeks)
- Blood Pressure Measures(12 weeks)
- body weight(12 weeks)
- height(12 weeks)
- waist and hip circumferences(12 weeks)
研究者
Mai Salah
principal investigator
Cairo University