Trichloroacetic acid chemical peel in anti-aging skin therapy in perimenopausal and postmenopausal wome

Not Applicable

Completed

• Conditions: Anti-aging skin therapy in perimenopausal and postmenopausal women; Skin and Connective Tissue Diseases

• Registration Number: ISRCTN41899475
• Lead Sponsor: The Academy of Physical Education in Katowice

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-09-28
• Study Completion: 2022-12-21
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 92

Inclusion Criteria

Current inclusion criteria as of 03/01/2023:

1st stage of intervention participant inclusion criteria:
1. Age of 40-58 years and menstruation for the group of perimenopausal women
2. Patient consent for the trial
3. Fitzpatrick skin type 2-3
4. Contraindications for chemical exfoliation (bacterial, viral or fungal infections, other inflammatory dermatoses such as psoriasis and topical dermatitis, topical retinoids treatment, keloid and scarring tendency)
5. No previous treatments of TCA chemical peels
6. No previous exfoliating and rejuvenating treatments within the previous 6 months, including chemical peels, microneedle radiofrequency, fractional ablation laser, microneedling therapy etc

2nd stage of intervention participant inclusion criteria:
1. Age 59-65 years for postmenopausal women
2. Patient consent for the trial
3. Fitzpatrick skin type 2-3
4. Contraindications for chemical exfoliation (bacterial, viral or fungal infections, other inflammatory dermatoses such as psoriasis and topical dermatitis, topical retinoids treatment, keloid and scarring tendency)
5. No previous treatments of TCA chemical peels
6. No previous exfoliating and rejuvenating treatments within the previous 6 months, including chemical peels, microneedle radiofrequency, fractional ablation laser, microneedling therapy etc

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Previous inclusion criteria:

1st stage of intervention participant inclusion criteria:
1. Age of 40-58 years and menstruation for the group of perimenopausal women
2. Patient consent for the trial
3. Fitzpatrick skin type 2-3
4. Contraindications for chemical exfoliation (bacterial, viral or fungal infections, other inflammatory dermatoses such as psoriasis and topical dermatitis, topical retinoids treatment, keloid and scarring tendency)
5. No previous treatments of TCA chemical peels
6. No previous exfoliating and rejuvenating treatments within the previous 6 weeks, including chemical peels, microneedle radiofrequency, fractional ablation laser, microneedling therapy etc

2nd stage of intervention participant inclusion criteria:
1. Age 59-65 years for postmenopausal women
2. Patient consent for the trial
3. Fitzpatrick skin type 2-3
4. Contraindications for chemical exfoliation (bacterial, viral or fungal infections, other inflammatory dermatoses such as psoriasis and topical dermatitis, topical retinoids treatment, keloid and scarring tendency)
5. No previous treatments of TCA chemical peels
6. No previous exfoliating and rejuvenating treatments within the previous 6 weeks, including chemical peels, microneedle radiofrequency, fractional ablation laser, microneedling therapy etc

Exclusion Criteria

Participant exclusion criteria (the same for the two experimental and control groups):
1. Contraindications to chemical exfoliation (local infections etc)
2. Malignancy
3. Pregnancy and breastfeeding
4. No possibility to participate in follow-up visits
5. History of mental illness and unrealistic expectations about the results of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified