Pulse EnRiched Food and Exercise Clinical Trials (PERFECT Project): Part 2 - Acute Effects of Pulse Ingredients in Food Products on Aerobic Endurance and Substrate Oxidation During Exercise, as Well as, the Blood Glucose, Insulin, Lactate and Food Intake Response Following an Endurance Exercise Session in Adults - Study 2
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Food Intake
研究概览
简要总结
The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. The investigators hypothesize that consumption of cereals containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. The investigators also hypothesize that consumption of cereals containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
- •Body Mass Index of 18.5-29.9 kg/m2
排除标准
- •Restrained eaters
- •Regularly skip breakfast
- •Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year
- •Those who are active (organized activities or athletic training at a high intensity; ≥ 150 minutes per week of moderate to vigorous physical activity)
- •Those unable to walk for an hour continuously
结局指标
主要结局
Food Intake
时间窗: at 240 minutes
Ad-libitum meal
Exercise intensity
时间窗: 60-120 minutes
Oxygen consumption measured during exercise at 3 time points
Insulin concentrations
时间窗: 0-240 minutes
Measured in blood using intravenous catheter. and Insulin will be measured by commercially available radioimmunoassay (RIA) kits
Plasma Glucose Concentrations
时间窗: 0-240 minutes
Measured in blood using intravenous catheter. Glucose will be determined by automated methods using Abbot Spectrum Clinical Chemistry-X Analyzer,
Subjective Appetite
时间窗: 0-240 minutes
Motivation-to-eat Visual Analog Scale questionnaire
次要结局
- Heart rate(60-120 minutes)
- Palatability measured by Visual Analog Scale questionnaire(5 and 260 minutes)
- Energy/fatigue measured by Visual Analog Scale questionnaire(0 - 240 minutes)
- Lactate concentration(60-120 minutes)
- Physical comfort measured by Visual Analog Scale questionnaire(0-240 minutes)
- Substrate Oxidation(60-120 minutes)