PERFECT Project - Part 2 - Study 2

Not Applicable

Completed

• Conditions: Obesity Prevention; Diabetes Prevention
• Interventions: Other: Pea Starch; Other: Pea fibre + pea starch + pea protein; Other: Control; Other: Pea fibre + pea starch; Other: Pea protein + pea starch; Other: Pea protein

• Registration Number: NCT02370927
• Lead Sponsor: University of Manitoba

Brief Summary

The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic exercise session, and 3) food intake two hours following the exercise session. The investigators hypothesize that consumption of cereals containing pulse ingredients 60 minutes before exercise will increase aerobic endurance (lower oxygen consumption), decrease carbohydrate oxidation (greater respiratory quotient), and a reduction in lactate production during compared to the same exercise session following the ingestion of a non-pulse food. The investigators also hypothesize that consumption of cereals containing pulse ingredients will lead to lower blood glucose, insulin, appetite and food intake, suggesting lower calorie compensation, following a 60-minute aerobic exercise session compared to the same exercise session following the ingestion of a non-pulse food.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2014-12-17
• Study First Submitted QC: 2015-02-24
• Study First Posted: 2015-02-25
• Study Start: 2016-05
• Primary Completion: 2017-07
• Study Completion: 2017-12
• Status Verified: 2018-07
• Last Update Submitted: 2023-01-25
• Last Update Posted: 2023-01-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Normoglycemic (<5.6 mmol/L) and normotensive (systolic blood pressure <140 mm Hg and diastolic blood pressure below < 90 mm Hg)
• Body Mass Index of 18.5-29.9 kg/m2

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Exclusion Criteria

• Restrained eaters
• Regularly skip breakfast
• Smokers
• Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year
• Those who are active (organized activities or athletic training at a high intensity; ≥ 150 minutes per week of moderate to vigorous physical activity)
• Those unable to walk for an hour continuously

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Cereal w/ pea starch	Pea Starch	Pea starch
Cereal w/ pea protein + pea fibre + pea starch:	Pea fibre + pea starch + pea protein	Pea protein + pea fibre + pea starch: 20g
Control	Control	100% Wheat Flour
Cereal w/ pea starch + pea fibre	Pea fibre + pea starch	Pea starch + pea fibre: 5g
Cereal w/ pea protein + pea starch	Pea protein + pea starch	Pea protein + pea starch: 10g
Cereal w/ pea protein	Pea protein	Pea protein

Primary Outcome Measures

Name	Time	Method
Food Intake	at 240 minutes	Ad-libitum meal
Exercise intensity	60-120 minutes	Oxygen consumption measured during exercise at 3 time points
Insulin concentrations	0-240 minutes	Measured in blood using intravenous catheter. and Insulin will be measured by commercially available radioimmunoassay (RIA) kits
Plasma Glucose Concentrations	0-240 minutes	Measured in blood using intravenous catheter. Glucose will be determined by automated methods using Abbot Spectrum Clinical Chemistry-X Analyzer,
Subjective Appetite	0-240 minutes	Motivation-to-eat Visual Analog Scale questionnaire

Secondary Outcome Measures

Name	Time	Method
Heart rate	60-120 minutes	To monitor exercise intensity and give a measure of fatigue (cardiovascular drift)
Palatability measured by Visual Analog Scale questionnaire	5 and 260 minutes	Food tasting
Energy/fatigue measured by Visual Analog Scale questionnaire	0 - 240 minutes	Estimate of energy expenditure
Lactate concentration	60-120 minutes	Measured before, during, and after exercise exercise at 3 time points
Physical comfort measured by Visual Analog Scale questionnaire	0-240 minutes	Contributions from energy intake
Substrate Oxidation	60-120 minutes	Respiratory quotient measured during exercise at 3 time points

Trial Locations

Locations (1)

Richardson Centre for Functional Foods and Nutraceuticals; 🇨🇦 Winnipeg, Manitoba, Canada