Intermittent pneumatic compression-induced changes in stroke volume predicts fluid responsiveness in Traumatic Brain injury and post-operative neurosurgery.
Phase 2
Completed
- Conditions
- Intermittent pneumatic compression (IPC) which augments significant increases of venous flow is suggested in neuro ICU patients when pharmacologic venous thromboembolism is contraindicated. Whether IPC induced changes in stroke volume (SV) predicts fluid responsiveness (FR) in patients with Traumatic Brain injury and post-operative neurosurgery is still unknown.Intermittent pneumatic compression, stroke volume, fluid responsiveness, Traumatic Brain injury, post-operative neurosurgery
- Registration Number
- TCTR20240419002
- Lead Sponsor
- Phramongkutklao hospital foundation
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
patients who were diagnosed Traumatic Brain injury and post-operative neurosurgery and admitted to surgical intensive care unit, Phramongkutklao Hospital Age more than 20-year-old and treatment continuously in Phramongkutklao hospital were included in this study.
Exclusion Criteria
Patients who refuse to treatment and to be subject, contraindication and complication for pneumatic leg compression, esophageal doppler and fluid challenge.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Hemodynamic variables in four time points 2 minutes increases in cardiac output (CO) more than 10 percentage from baseline CO following fluid bolus
- Secondary Outcome Measures
Name Time Method Cut-off point of percentage of changes in CO 2 minutes after perform fluid responsiveness Cardiac output following IPC to predict fluid responsiveness