MedPath

Telephone Counseling for Pregnant Smokers

Phase 3
Completed
Conditions
Smoking
Interventions
Behavioral: Telephone counseling
Behavioral: Self-help materials
Registration Number
NCT02144883
Lead Sponsor
University of California, San Diego
Brief Summary

This purpose of the study was to investigate the efficacy of telephone counseling to help pregnant women quit smoking. The investigators tested two hypotheses: 1) telephone counseling increases the overall cessation rate during pregnancy, and 2) the counseling effects can be maintained postpartum.

Detailed Description

Smoking during pregnancy increases the risk of low birth weight, premature delivery, fetal and infant death, and children's developmental problems. It is also associated with significant economic costs. Telephone cessation quitlines have been suggested as one good way to reach pregnant smokers.

This randomized controlled trial was embedded into a free statewide telephone cessation quitline in California. The primary component of the intervention was telephone counseling using a structured protocol developed specifically for the pregnant population. The counseling consisted of nine counseling sessions.

A secondary component of the intervention was the mailed materials. Following enrollment in the study all subjects (control and intervention) received a self-help quit kit for pregnant smokers and fact sheets on second-hand smoke and additional tips for quitting while pregnant. Subjects in the counseling intervention group received five additional mailings. These mailings were designed to remind them of their commitment to quitting and of the presence of counseling support if they needed help.

Prior to 36 weeks gestation (in the third trimester), 2-months postpartum, and 6-months postpartum we conducted a brief telephone survey to assess smoking status. The information obtained allowed us to determine 30-day prolonged abstinence rates.

Prior to 36 weeks gestation (in the third trimester), the investigators sent a kit and requested saliva samples be mailed back to biochemically verify smoking status by testing for cotinine and nicotine byproducts.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
1173
Inclusion Criteria
  • Current smoker willing to quit within one month
  • Recent quitters
  • First time quitline caller
  • Less than 27 weeks gestation
  • English and/or Spanish speaking
  • Valid phone number
  • Valid address
  • Gave consent to participate in study and evaluation
Exclusion Criteria
  • Active psychiatric disorder
  • Substance or alcohol abuse
  • Had been in recovery from alcohol or other substances for less than 6 months
  • Planned to use pharmacotherapy
  • Insufficient contact information

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Telephone Counseling and MaterialsSelf-help materialsSubjects received up to 9 telephone counseling calls plus self-help quit kit and 5 additional mailings
MaterialsSelf-help materialsSelf-help materials mailed to subjects home.
Telephone Counseling and MaterialsTelephone counselingSubjects received up to 9 telephone counseling calls plus self-help quit kit and 5 additional mailings
Primary Outcome Measures
NameTimeMethod
30 days prolonged abstinence6-months postpartum

Conducted a brief telephone survey to assess smoking status. The information obtained allowed us to determine 30-day prolonged abstinence rates.

Secondary Outcome Measures
NameTimeMethod
Percentage of smokers making a 24-hour quit attempt6-months postpartum

During evaluation call subjects were asked if they had made a quit attempt that lasted at least 24 hours.

Relapse curve based on quit attemptSeven months post enrollment

Kaplan-Meier analysis on the quit attempts over a 6 month period.

7-day cotinine verified abstinence<36 weeks gestation

Subjects were asked to submit a saliva sample. This sample was sent to a laboratory to test the cotinine level.

30 days prolonged abstinence2-months postpartum

Conducted a brief telephone survey to assess smoking status. The information obtained allowed us to determine 30-day prolonged abstinence rates.

Safety Issue? (FDAAA) No

Trial Locations

Locations (1)

University of California San Diego California Smokers' Helpline

🇺🇸

San Diego, California, United States

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