Myocardial tissue characterisation in left ventricular hypertrophy using echocardiography and cardiac magnetic resonance.

Not Applicable

• Conditions: Aortic Stenosis; Systemic Hypertension; Cardiovascular - Hypertension; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12611000156987
• Lead Sponsor: Professor Joesph Selvanayagam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-02-09
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Cohort 1. Patients with history of aortic stenosis.
Cohort 2. patients with history of systemic hypertension
Cohort 3. healthy subjects, no history of AS or hypertension

Exclusion Criteria

Known cardiovascular disease
Known peripheral vascular disease
Hypercholesterolemia (total cholesterol > 6mmol/L)
Diabetes (type I or II)
Metabolic syndrome and a BMI of < 30
Standard MRI contraindications, including permanent pacemaker, implantable defibrillator, severe claustrophobia.
Renal impairment (eGFR < 60ml/min) will be an exclusion criterion from the administration of gadolinium

Study & Design

• Study Type: Observational
• Study Design: Not specified