An Affective Intervention to Reverse the Biological Residue of Low Childhood SES
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 113
- 试验地点
- 2
- 主要终点
- Change in meditation time (Self-reported meditation time recorded daily)
研究概览
简要总结
Growing up in a low-income household has been shown to increase risk for, and susceptibility to many illnesses.The purpose of the study is to test an affective intervention for reversing biological risk factors, as related to childhood adversity, in midlife.
Participants will be asked to make two lab visits; attend six weekly, 1-hour meditation classes; as well as complete brief online daily surveys for 11 weeks, five biweekly surveys, and two 30-minute surveys prior to each lab visit. During the lab visits, participants will have their psychophysiology monitored for heart rate, blood pressure, respiration, and pulse. Participants will also have their blood drawn.
All surveys and questionnaires inquire about participants' current demographics, family history, perceptions about life and well-being, physical health, and monetary choices.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 35 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •fluent in written and spoken English
- •have daily access to internet and a computer
排除标准
- •engaged in regular meditation practice, either recently or in the past
- •previously participated in a meditation study
- •have allergies to adhesive materials (includes latex)
结局指标
主要结局
Change in meditation time (Self-reported meditation time recorded daily)
时间窗: Weeks 3, 4, 5, 6, 7, 8, 9 ,10, 11, 12
Self-reported meditation time recorded daily.
次要结局
- Cardiac vagal tone (Respiration and echocardiogram measured with respiration band and 2-lead electrode placement)(Week 0, Week 12)
- Leukocyte basal gene expression (evaluated through blood samples)(Week 0, Week 12)
- Levels of mistrust (Self-report questionnaire measure of hostility using 9-item Cooke-Medley scale)(Week 0, Week 12)
- Temporal Discounting (Monetary choice questionnaire to assess impulsive decision-making)(Week 0, Week 12)
研究者
Barbara L. Fredrickson, PhD
Kenan Distinguished Professor
University of North Carolina, Chapel Hill