Assessment of breathing parameters using single-channelled breathing tube in surgeries for esophageal cancer

Not yet recruiting

• Conditions: Malignant neoplasm of esophagus, (2) ICD-10 Condition: C169||Malignant neoplasm of stomach, unspecified,

• Registration Number: CTRI/2025/04/083923
• Lead Sponsor: SANJANA S

Brief Summary

After obtaining approval from the Institutional Ethics Committee, patients with a known diagnosis of CA oesophagus/ stomach who are posted for VATS esophagectomy at our institution will be recruited. A written informed consent from the patient will be obtained and demographic information about each patient including age, sex, weight, and height will be obtained from the charts. On the day of the surgery, the patient will be induced as per the choice of the concerned anaesthesiologist. The initial ventilation mode shall be kept as pressure controlled to achieve tidal volume of 5 ml/kg. Respiratory rate shall be titrated to maintain ETCo2 between 35 and 45. Post induction, information such as the duration of surgery, approach (Ivor Lewis/ McKewon) ventilatory parameters (tidal volumes, respiratory rate, peak pressures, PEEP, compliance, FiO2, oxygen saturation, end-tidal carbon dioxide), capnothorax parameters (insufflation pressure, flow rate), surgeons’ comfort about visibility of structures by using a 5 point Likert scale, and post-operative events (ICU stay, respiratory complications within one-week prolonged hospital stay) will also be noted.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-03-25
• Study Start: 2025-04-14

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Adult patients (18 years and above) who will undergo video-assisted thoracoscopic oncological oesophageal surgeries (CA stomach/ CA oesophagus) in the study period.

Exclusion Criteria

VATS converted to open esophagectomy, pregnant women, persons with intellectual disabilities.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate mean tidal volume during one lung ventilation with single lumen tube during the period of capnothorax during VATS	Beginning of surgery, After capnothorax initiation- 0 min, 30 min, 60 min, 90 min, 120 min, 180 min, 210 min, End of surgery

Secondary Outcome Measures

Name	Time	Method
- To evaluate other ventilatory parameters during capnothorax with TLV in VATS	- To assess surgeons’ comfort in visibility during capnothorax

Trial Locations

Locations (1)

KASTURBA MEDICAL COLLEGE MANIPAL; 🇮🇳 Udupi, KARNATAKA, India

KASTURBA MEDICAL COLLEGE MANIPAL

🇮🇳Udupi, KARNATAKA, India

SANJANA S

Principal investigator

09952612396

sanjanasubbiah44@gmail.com