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临床试验/CTRI/2025/04/083923
CTRI/2025/04/083923尚未招募不适用

A PROSPECTIVE STUDY ASSESSING VENTILATORY PARAMETERS WITH SINGLE LUMEN ENDOTRACHEAL TUBE IN VIDEO-ASSISTED THORACOSCOPIC OESOPHAGEAL ONCOLOGICAL SURGERIES

SANJANA S1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2025年4月14日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
50
试验地点
1
主要终点
To evaluate mean tidal volume during one lung ventilation with single lumen tube during the period of capnothorax during VATS

研究概览

简要总结

After obtaining approval from the Institutional Ethics Committee, patients with a known diagnosis of CA oesophagus/ stomach who are posted for VATS esophagectomy at our institution will be recruited. A written informed consent from the patient will be obtained and demographic information about each patient including age, sex, weight, and height will be obtained from the charts. On the day of the surgery, the patient will be induced as per the choice of the concerned anaesthesiologist. The initial ventilation mode shall be kept as pressure controlled to achieve tidal volume of 5 ml/kg. Respiratory rate shall be titrated to maintain ETCo2 between 35 and 45. Post induction, information such as the duration of surgery, approach (Ivor Lewis/ McKewon) ventilatory parameters (tidal volumes, respiratory rate, peak pressures, PEEP, compliance, FiO2, oxygen saturation, end-tidal carbon dioxide), capnothorax parameters (insufflation pressure, flow rate), surgeons’ comfort about visibility of structures by using a 5 point Likert scale, and post-operative events (ICU stay, respiratory complications within one-week prolonged hospital stay) will also be noted.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Adult patients (18 years and above) who will undergo video-assisted thoracoscopic oncological oesophageal surgeries (CA stomach/ CA oesophagus) in the study period.

排除标准

  • VATS converted to open esophagectomy, pregnant women, persons with intellectual disabilities.

结局指标

主要结局

To evaluate mean tidal volume during one lung ventilation with single lumen tube during the period of capnothorax during VATS

时间窗: Beginning of surgery, After capnothorax initiation- 0 min, 30 min, 60 min, 90 min, 120 min, 180 min, 210 min, End of surgery

次要结局

  • - To evaluate other ventilatory parameters during capnothorax with TLV in VATS(- To assess surgeons’ comfort in visibility during capnothorax)

研究者

发起方
SANJANA S
申办方类型
Other [self]

研究点 (1)

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