Ozone Therapy in Endodontic Practice, in Vivo Study
- Conditions
- Primary Apical Periodontite
- Interventions
- Registration Number
- NCT00946634
- Lead Sponsor
- University of Sao Paulo
- Brief Summary
The ozone therapy has been coming up as a new therapeutic modality. Medicine has been practicing since XIX century and counted great results. It is indicated for the treatment of 260 different pathologies. The researches in Dentistry has showed promising results, indicating a wide spread action in whole dental specialties. The great oxidative power of ozone provides a great antimicrobial effect and it increases the adenosine triphosphate (ATP) synthesis that can be considered as a general improvement of the cell metabolism, which can potentize the repair process. Thus, these facts justify the present study which will assess the increase of speed of apical periodontite repair.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
- Healthy patients
- Radiographic evidence of apical periodontite
- No previous root canal treatment
- Unhealthy patients
- Regular response to sensibility test
- Previous root canal treatment
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Aqueous Ozone Aqueous Ozone Endodontic protocol preconized by University of Sao Paulo associated to Aqueous ozone 40mg/L Control Control (no last irrigation) Regular endodontic protocol preconized by University of Sao Paulo Ozone Gas Ozone Endodontic protocol preconized by University of Sao Paulo associated to ozone gas 40 mg/L
- Primary Outcome Measures
Name Time Method Acceleration in repair by healing of apical periodontite 3 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Fundação para o Desenvolvimento Científico e Tecnológico da Odontologia of University of Sao Paulo
🇧🇷Sao Paulo, SP, Brazil