Dynamic spasticity in children with Cerebral Palsy

• Conditions: Brain damage; Cerebral Palsy; 10010335

• Registration Number: NL-OMON30007
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Patients:
-Clinical diagnosis of Spastic Cerebral Palsy
-Diplegic or hemiplegic
-Age: between 6 and 12 years of age
-Male and female
-Independent walkers without walking aids (with or without AFO, GMFCS classification I or II (gross motor function classification system, (Wood and Rosenbaum, 2000)) ;Healthy controls
-Age-matched to CP

Exclusion Criteria

Patients:
-Prior multilevel surgery, SDR or baclophen treatment.
-Prior BTX-A < 16 weeks
-Orthopaedic deformities that have major effect on gait
-The child*s movement pattern is mainly dyskinetic / ataxic
-Additional disorders (other than CP) that influence gait
-Parents or guardians and child do not understand the Dutch or English language well enough to take part in this project ;Healthy controls
-Any (known) deviation that may influence gait
-Parents or guardians and child do not understand the Dutch or English language well enough to take part in this project

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome measure is the difference in dynamic spasticity (*velocity<br /><br>dependent muscle activation during gait*) between healthy children and children<br /><br>with CP.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable</p><br>