Erector Spinae Plane Block with Dexmedetomidine and Bupivacain Versus Dexamethasone and Bupivacain for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries

Phase 1

Not yet recruiting

• Conditions: Analgesia, Postoperative

• Registration Number: NCT06658418
• Lead Sponsor: Loay Gamal

Brief Summary

To compare the analgesic effect of dexmedetomidine combined with bupivacaine versus dexamethasone combined with bupivacaine for ultrasound-guided ESPB for postoperative pain control in patients scheduled for abdominal surgeries

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-10
• Study First Submitted: 2024-10-24
• Study First Submitted QC: 2024-10-24
• Last Update Submitted: 2024-10-24
• Study First Posted: 2024-10-26
• Last Update Posted: 2024-10-26
• Study Start: 2024-11-01
• Primary Completion: 2026-11-01
• Study Completion: 2026-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

Age :18 years old and older. Patients undergoing open abdominal surgery.

Exclusion Criteria

1. Patient refusal
2. known sensitivity or contraindication to any of study drugs
3. contraindications for local anesthesia
4. Patients with local infection at site of puncture
5. uncooperative patients
6. history of psychological disorders or chronic pain and significant liver or renal disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
VAS score	at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.	pain intensity using VAS score

Secondary Outcome Measures

Name	Time	Method
the time for requirement of first morphine dose	at 30 minutes, 2, 4, 6, 8, 12, 16, 20, and 24 hours postoperative.	the time for requirement of first morphine dose (hours)