Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects

Phase 4

Completed

• Conditions: Periodontitis, Adult
• Interventions: Biological: advanced PRF

• Registration Number: NCT05730153
• Lead Sponsor: October University for Modern Sciences and Arts

Brief Summary

in this clinical trial, patients with periodontal defects will be treated with advanced platelet-rich fibrin in conjunction with open debridement

Detailed Description

two groups of patients with suprabony defects, one will be treated with advanced platelet-rich fibrin in conjunction with open debridement and the other will be treated with open debridement alone. subjects will be evaluated for evidence of bone formation after 6 months of therapy

Study Timeline

• Study Start: 2021-11-21
• Primary Completion: 2022-01-27
• Study Completion: 2022-07-26
• Status Verified: 2023-02
• Study First Submitted: 2023-02-07
• Study First Submitted QC: 2023-02-07
• Study First Posted: 2023-02-15
• Last Update Submitted: 2023-03-23
• Last Update Posted: 2023-03-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• patients with periodontal suprabony defects.

Exclusion Criteria

• pregnant females.
• smokers.
• systemic disease that contraindicate surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
group 1	advanced PRF	-
group 2	advanced PRF	-

Primary Outcome Measures

Name	Time	Method
clinical evaluation	6 months	Rate of probing pocket depth reduction

Secondary Outcome Measures

Name	Time	Method
radiographic evaluation	6 months	Rate of bone formation by digital radiography

Trial Locations

Locations (1)

Al-Azhar University, Faculty of Dentistry; 🇪🇬 Cairo, Egypt