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Tackling freezing of gait in Parkinson's disease

Conditions
Parkinson's disease
10028037
Registration Number
NL-OMON30278
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
30
Inclusion Criteria

Parkinson's disease
Ability to walk without help for 10 minutes on a treadmill

Exclusion Criteria

atypical hypokinetic rigid syndrome
cognitive impairment (Mini Mental State Examination (MMSE) score <24)
other cause of gait disorder (neurological, muscles, bones, visual, balance)
major psychiatric disease
major comorbidity

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Visual assessment of videotaped gait performance on the treadmill will be used<br /><br>as gold clinical standard; primary outcome is occurence of freezing of gait.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>We propose an elaborate and sophisticated battery of outcome measures to<br /><br>optimise detection of subtle FOG manifestations. Measures in both experiments<br /><br>will include kinematics of individual body segments, reactive forces under the<br /><br>feet and telemetric (wireless) surface electromyography of eight muscles.</p><br>
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