Assessment of nutritional deficiencies post treatment in children with nutritional rickets
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Proportion of children treated for nutritional rickets with low vitamin D levels(Less than 20 ng per ml)
研究概览
简要总结
As the cause of rickets is predominantly nutritional deficiency, a detailed nutritional assessment of other micronutrients and macronutrients will be an essential component of wholesome management. Recent UNICEF5 data also shows that micronutrient deficiencies affect more than 340 million children under 5 globally, with India having 38.4 per cent children with stunting.The current study was planned to assess the nutritional intake and micronutrient deficiencies in children who have been treated for nutritional rickets.The study will enrol 90 previously treated children with rickets to analyse their current macronutrient and micronutrient intake. Blood sample will be taken to estimate the levels of calcium, phosphorus, ALP, vitamin D, parathyroid hormone, iron, folate and vitamin C. Any child who is found with calcium and/or vitamin D deficiency will be treated as per standard guidelines.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 6.00 Month(s) 至 5.00 Year(s)（—）
- 性别
- All
入选标准
- •Children of age 6 months to 5 years who were treated for nutritional rickets in the preceding 12-24 months.
排除标准
- •Children with malabsorption syndrome.
- •Children with any other chronic systemic illness.
- •Children who received more than or equal to 60,000 IU of Vitamin D in the last 6 months.
结局指标
主要结局
Proportion of children treated for nutritional rickets with low vitamin D levels(Less than 20 ng per ml)
时间窗: 1 year
次要结局
- Mean daily macronutrient (Carbohydrate, Protein, Fat) and micronutrient (Vitamin D, Vitamin C, Calcium and Iron) intake.(1 year)
- Anthropometric assessment – Weight for age Z score, Height/Length for age Z score, Weight for Height Z score, head circumference and Mid Upper Arm Circumference (MUAC) Z score.(1 year)
- Proportion of patients with scurvy, anaemia, vitamin B deficiency(1 year)
- Mean Calcium, Phosphorus, ALP, PTH, Iron, Vitamin C, Folate, Ferritin, S. Albumin levels(1 year)
研究者
Veanupreethaa V S
Maulana Azad Medical College