Simplified evaluatiion of renal functional reserve

Not Applicable

• Conditions: CKD patients; renal functional reserve

• Registration Number: JPRN-jRCT1040210152
• Lead Sponsor: Isobe Shinsuke

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-02-23
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Healthy volunteer
1. 20-80 years old
2. Individuals without CKD
3. Individuals with written informed consent

CKD patients
1. 20-80 years old
2. eGFR < 60ml/min/1.73m2, or evidence of proteinuria and/or hematuria
3. CKD patients with written informed consent

Exclusion Criteria

Health volunteer
1. Those who compricated or are being treater other disease
2. Pregnant , lactating, or menstruating women
3. Those who are judged by the principal investigator or the investigator to be unsuitable for participation in the research

CKD patients
1. Patients requiring hemodialysis or peritoneal dialysis
2. Sever acidosis
3. Congestive heart failure
4. Hyponatremia
5. Pregnant , lactating, or menstruating women
6. Treated with SGLT2 inhibitor, diuretics, or renin-angiotensin inhibitors.
7. Those who are judged by the principal investigator or the investigator to be unsuitable for participation in the research

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
We compare the correlation between the renal functional reserve which evaluated the conventional method and the simple method, for healthy volunteer and patients with chronic kidney disease.

Secondary Outcome Measures

Name	Time	Method
Multiple linere regression analyses will be performed to evaluate the relationship the renal functional reserve using the simplified method and that evaluating the conventional method.