Diagnostic Performance of Point of Care Ultrasound to Identify Intestinal Obstruction

• Conditions: Bowel Obstruction

• Registration Number: NCT04848415
• Lead Sponsor: Nantes University Hospital

Brief Summary

As reported in previous studies, Point-of-Care Ultrasound (POCUS) has good performance for the diagnosis of bowel obstruction even when compared with CT. This inexpensive, radiation-free tool is available in a majority of ED. It is performed at the patient's bedside with immediate results. The learning curve allows Emergency Physicians (EP) to perform this exam after a relative brief training period.

The investigators aim to investigate the ability of POCUS performed before CT to exclude the diagnosis of bowel obstruction in patients admitted for abdominal pain.

Detailed Description

Bowel obstruction (BO) is frequently suspected in the Emergency Department (ED). Computed Tomography (CT) is commonly used to diagnose this disease. However, CT is not always available in real-time, requires technician times, is associated with increased cost and exposes patients to radiations.

The researchers will investigate the diagnosis performances of POCUS for the diagnosis of BO with comparison with CT which will be considered as the gold standard. The wain objective will be the ability to exclude the diagnosis of BO, the main criteria being the negative predictive value. The secondary objectives will be the diagnosis performances (sensitivity, specificity, positive predictive value), duration and difficulty of POCUS

Study Timeline

• Study First Submitted: 2021-02-15
• Status Verified: 2021-04
• Study First Submitted QC: 2021-04-16
• Last Update Submitted: 2021-04-16
• Study First Posted: 2021-04-19
• Last Update Posted: 2021-04-19
• Study Start: 2021-05-01
• Primary Completion: 2022-05-01
• Study Completion: 2022-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Negative predictive value of POCUS	Through ED stay, up to 24 hours	Negative predictive value of POCUS for the diagnosis of bowel obstruction compared with computed tomography result

Secondary Outcome Measures

Name	Time	Method
Sensitivity of POCUS for the diagnosis of bowel obstruction	Through ED stay, up to 24 hours	sensitivity of POCUS, for the diagnosis of bowel obstruction compared with computed tomography result
Specificity of POCUS for the diagnosis of bowel obstruction	Through ED stay, up to 24 hours	specificity of POCUS, for the diagnosis of bowel obstruction compared with computed tomography result
Positive predictive value of POCUS for the diagnosis of bowel obstruction	Through ED stay, up to 24 hours	Positive predictive value