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A monitoring study to investigate the effects of soft meals on weight gain and grip strength in elderly volunteers

Not Applicable
Conditions
Elderly individuals aged 65 years old or older
Registration Number
JPRN-UMIN000029873
Lead Sponsor
InCROM Inc
Brief Summary

Among 30 subjects, a total of 28 finished the trial, The change in body weight from the start of the study to the end was -0.45 +/- 0.75 kg (Mean+/-SD, the same hereinafter), 95% confidence interval (CI) on both sides was [-0.74, -0.15], P=0.0041, showing a significant decrease. Through the analysis of the individual weight change, body weight increased in only 6 subjects, equaled in 3 subjects, and decreased in 19 subjects. More than 1 kg of body weight decreased in 6 subjects, whereas that increased in none. The maximum change in body weight was 0.8 kg, and minimum -2.7 kg. The change in BMI was -0.12 +/- 0.30, and the 95% CI on both sides was [-0.24, -0.01], P=0.0384, showing a significant decrease. No significant changes in grip strength, serum total protein, or albumin were observed. The change in grip strength was 0.1 +/- 1.6 kg, and 95% CI on both sides was [-0.5, 0.8], P=0.6458. The change in serum total protein was -0.07 +/- 0.27 g/dL, 95% CI on both sides was [-0.17, 0.04], P=0.1872. The change in albumin was -0.02 +/- 0.18 g/dL, 95% CI on both sides was [-0.09, 0.05], P=0.6131. No significant adverse events were observed.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Not provided

Exclusion Criteria

Diabetic patients History of previous or present illness that interferes with ethical conduct of the research as determined by the investigator, e.g., hepatic or renal disorder; gastrointestinal, cardiovascular, respiratory, endocrine, metabolic, nervous, or psychological disease Those with extremely lowered appetite Those who possibly have allergy to test diets History of previous or present drug or alcohol dependence Those who live in a welfare facility

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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