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Clinical Trials/NCT04876001
NCT04876001
Completed
Not Applicable

Effects of Nurse-Led Brief Behavioral Treatment for Insomnia Following Stroke: A Randomized Controlled Trial

Taipei Medical University1 site in 1 country42 target enrollmentNovember 1, 2022
ConditionsInsomnia

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Insomnia
Sponsor
Taipei Medical University
Enrollment
42
Locations
1
Primary Endpoint
Sleep parameters ("change" is being assessed)
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The current study aims to compare face-to-face and internet-based nurse-led BBTI compare to a wait-list conditions in the stroke population. This study is a parallel, three-arm, randomized controlled trial (RCT). Each participant will be randomized into one of the treatment arms; face-to-face BBTI, internet-based BBTI, and waiting-list. The BBTI, emphasizes behavioral aspects of insomnia care, arises from techniques of sleep restriction and stimulus control. The face-to-face and internet-based BBTI have equivalent content based on the standard portion. All participants will be asked to fill the online questionnaires at weeks 0 (baseline), 1 (mid-treatment), 2 (post-treatment), 4, and 12 (follow up). After the final follow-up, the waiting-list participants will be allowed to join the internet-based BBTI treatment. Our hypotheses are that patients with stroke who receive face-to-face or internet-based BBTI, compared to a wait-list condition, will experience fewer insomnia complaints.

Detailed Description

Post-stroke insomnia is a common complaint with prevalence rates remain high. Patients suffering from insomnia following stroke could impair their health-related quality of life and negative rehabilitation outcomes. Identifying effective treatment in managing post-stroke insomnia has become clinically relevant. Brief behavioral therapy for insomnia (BBTI), a 4-section of treatment for insomnia, has similar treatment components with CBTI, with the exception of cognitive therapy. Previous evidence found that both BBTI and CBTI have comparable effects on improving sleep quality and consolidation. Existing literature has suggested that BBTI was effective on mitigating primary and comorbid insomnia. Nonetheless, thus far, no study has explored its effects in stroke population. Of note, BBTI still requires certain contact with therapists. To enhance the widespread dissemination of BBTI, it is important to establish the internet-based BBTI treatment model (more flexible time schedule) to target more populations with insomnia. The recent study of the online tailored BBTI has proven the comparable effects to reduce insomnia severity in the general population. However, no study investigates the efficacy of internet-based nurse-led BBTI in the stroke population.

Registry
clinicaltrials.gov
Start Date
November 1, 2022
End Date
February 28, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hsiao-Yean Chiu

Principal Investigator

Taipei Medical University

Eligibility Criteria

Inclusion Criteria

  • Had diagnosed with stroke for at least 3 months (chronic phase)
  • Had NIHSS score \< 6
  • Complain insomnia symptom based on the score of ISI\> 7
  • Having sufficient cognitive function to complete tasks,
  • Able to access to internet

Exclusion Criteria

  • The people receiving BBTI and other psychological treatment for insomnia
  • Doing shift work
  • Having psychiatric disorders
  • Being pregnant or breastfeeding
  • Having other sleep disorders (e.g., sleep apnea)
  • Drugs or alcohol abuse,
  • Serious or unstable medical condition prior to the study

Outcomes

Primary Outcomes

Sleep parameters ("change" is being assessed)

Time Frame: Baseline and up to week 4 (immediately after the intervention)

The Sleep Diary (SD) will be used to measure the subjective sleep parameters, including total sleep time, sleep onset latency, wake after sleep onset, sleep efficiency, and sleep quality. The good result such as total sleep time between 6-8 hours, sleep onset latency less than 30 minutes, wake after sleep onset less than 30 minutes, sleep efficiency greater than 85%, and sleep quality is good.

Insomnia severity ("change" is being assessed)

Time Frame: Baseline, week 2 (during the intervention), week 4 (immediately after the intervention), and week 12 (follow up).

Insomnia Severity Index (ISI) will be used to measure the concept of insomnia symptoms. The total score is 0-28, where cutoff point score\> 7 indicated as the presence of insomnia. The higher scores indicate severe condition.

Secondary Outcomes

  • Depression ("change" is being assessed)(Baseline, week 2 (during the intervention), week 4 (immediately after the intervention), and week 12 (follow up).)
  • Anxiety ("change" is being assessed)(Baseline, week 2 (during the intervention), week 4 (immediately after the intervention), and week 12 (follow up).)
  • Fatigue ("change" is being assessed)(Baseline, week 2 (during the intervention), week 4 (immediately after the intervention), and week 12 (follow up).)
  • Sleepiness ("change" is being assessed)(Baseline, week 2 (during the intervention), week 4 (immediately after the intervention), and week 12 (follow up).)

Study Sites (1)

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