The Effect of Different Muscle Training on Activities of Daily Living in COPD

Not Applicable

• Conditions: Anxiety; Quality of Life

• Registration Number: NCT05501457
• Lead Sponsor: Hitit University

Brief Summary

Chronic obstructive pulmonary disease (COPD) contributes significantly to global morbidity and mortality; It is a disease that affects an estimated 210 million people worldwide and is the third most common cause of death. COPD is identified by persistent airflow limitation and is associated with progressively worsening lung function, dyspnea, health-related quality of life (HRQOL), and impaired exercise capacity. Poor exercise capacity is a common finding of chronic obstructive pulmonary disease (COPD). Central cardiopulmonary factors, respiratory muscle dysfunction, gas exchange abnormalities, and skeletal muscle dysfunction all play a role in limiting exercise capacity The aim of this study is to investigate the effects of neuromuscular electrical stimulation applied to different muscle groups (quadriceps femoris and gastrocnemius muscles) on exercise performance and quality of life in patients with stable COPD and compare it with standard treatment.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-07-15
• Status Verified: 2022-08
• Study First Submitted: 2022-08-09
• Study First Submitted QC: 2022-08-11
• Last Update Submitted: 2022-08-11
• Study First Posted: 2022-08-15
• Last Update Posted: 2022-08-15
• Primary Completion: 2022-10-01
• Study Completion: 2022-11-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• Being between 18-75 years old,
• Diagnosed as group B stable COPD according to GOLD criteria by a pulmonologist,
• PaO2 >55 mm Hg, PaCO2 <45 mmHg in room air.

Exclusion Criteria

• Exacerbation,
• Cor pulmonale or respiratory muscle fatigue (abdominal paradoxical breathing),
• Cardiac instability (with acute MI, congestive heart failure, or uncontrollable arrhythmia),
• Musculoskeletal disorder (conditions affecting exercise ability),
• Difficulty communicating.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
6 Minute Walk Test (6 MWT):	4 weeks	they could walk for 6 minutes, according to heart rate, blood pressure, respiratory rate, finger oxygen saturation, the walking distance at the end of walking, and dyspnea score according to the Modified Borg Scale (MBS) at the beginning and end of walking was recorded. Change from baseline 6 Minute walking performance after 4 weeks will be examined.

Secondary Outcome Measures

Name	Time	Method
Beck Depression Inventory (BDI):	4 weeks	It measures the behavioral findings of depression in adolescents and adults. Change from baseline depression status after 4 weeks will be examined.
St. George's Respiratory Questionnaire (SGRQ):	4 weeks	This questionnaire was developed specifically to determine the severity of the disease in COPD and asthma. Change from baseline severity of the disease after 4 weeks will be examined.
Modified Borg Scale (MBS):	4 weeks	It consists of 10 items that define the severity of dyspnea according to their degrees. Change from baseline dyspnea after 4 weeks will be examined.

Trial Locations

Locations (1)

Hititi University Sungurlu Vocational School; 🇹🇷 Corum, Turkey