JPRN-UMIN000017440CompletedPhase 4
In methotrexate resistant rheumatoid arthritis, switching methotrexate to tofacitinib versus adding tofacitinib to methotrexate, open labeled, multicenter randomized non-inferiority study. - RAXEL study
Graduate School of Medicine and School of Medicine, Chiba University the department of allergy and clinical immunology0 sites134 target enrollmentStarted: May 7, 2015Last updated:
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 134
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18years-old to 90years-old (—)
- Sex
- All
Inclusion Criteria
- Not provided
Exclusion Criteria
- •(1)The patient suffering from autoimmune disease With the exception of the Sjogren's syndrome and thyroid disease. (2)Active tuberculosis, HIV, HBV or HCV infection has coexist. (3)There is a pregnancy hope. (4)There is a history of malignancy within the past 5 years. (5)There is a history of tuberculosis infection within the past one year. (6)There is a potential comorbidities requiring Intravenous glucocorticoid, Oral glucocorticoid, Immunosuppressant, biologics, Plasma exchange or IVIG during the study period. (7)Other, who is investigator or test sharing doctor was judged unsuitable to safely carry out the present study.
Investigators
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