Effect of glutamine supplementation on intestinal homeostasis and RUNX3 methylation in ulcerative colitis
Not Applicable
Recruiting
- Conditions
- K51Ulcerative colitis
- Registration Number
- DRKS00028618
- Lead Sponsor
- Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Grant no. 502-14-15200100-45007 from the PUMS statutory subsidy for young scientists
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Control group - Age 8-18. Informed consent of the study participant/legal guardian.
Study group - Age 8-18. Minimum 30 kg body weight. Diagnosis of UC. Introduction of biological treatment of UC (0.2 regimen). Informed consent of the study participant/legal guardian.
Exclusion Criteria
Control group - Significant disease burden (serious general condition, chronic disease). Antibiotic cycle in the last six months. Pregnancy. Withdrawal of informed consent.
Study group - Serious general condition. Surgical intervention within the gastrointestinal tract. Pregnancy. Non-compliance. Withdrawal of informed consent.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change from baseline in serum laboratory markers in children with ulcerative colitis (blood sampling before and after a 14-day intervention, serum, enzyme-linked immunosorbent assay (ELISA)).
- Secondary Outcome Measures
Name Time Method