NCT05734534
Recruiting
Not Applicable
Effects of BFR Interventions on Muscle Function and Adaptations in Healthy Individuals and Individuals With COPD
Morten Hostrup, PhD1 site in 1 country105 target enrollmentMarch 1, 2023
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Healthy
- Sponsor
- Morten Hostrup, PhD
- Enrollment
- 105
- Locations
- 1
- Primary Endpoint
- Muscle strength
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
The purpose of the study is to investigate the effect of different blood flow restriction (BFR) interventions on muscle function and adaptations both in healthy well-trained individuals and individuals diagnosed with COPD.
Investigators
Morten Hostrup, PhD
Associate Professor
University of Copenhagen
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Muscle strength
Time Frame: Change assessed from before to after the intervention (6 weeks in study A, on average 7 days in study B)
Maximal voluntary isometric contraction of m. quadriceps femoris
Secondary Outcomes
- Maximal oxygen consumption(Change assessed from before to after the 6 week intervention)
- Skeletal muscle mitochondrial respiration(Change assessed from before to after the intervention (6 weeks in study A, on average 7 days in study B))
- Fiber cross-sectional area(Change assessed from before to after the intervention (6 weeks in study A, on average 7 days in study B))
- Functional exercise capacity(Change assessed from before to after the 6 week intervention (only in individuals with COPD))
- Satellite cells(Change assessed from before to after the intervention (6 weeks in study A, on average 7 days in study B))
- Lean mass(Change assessed from before to after the 6 week intervention)
- Myonuclei(Change assessed from before to after the intervention (6 weeks in study A, on average 7 days in study B))
Study Sites (1)
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