Does endometrial scratching in women with implantation failure after a first IVF/ICSI cycle lead to lower costs due to a reduction in the number of subsequent IVF/ICSI cycles needed to achieve a live birth? - SCRaTCH

niversitair Medisch Centrum Utrecht0 个研究点目标入组 933 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•1. Female age 18-43 years
•2. Implantation failure (IF) defined as the absence of a clinical pregnancy occurring after a full first ART cycle, where at least one embryo has been transferred, in either the fresh or subsequent frozen/thaw cycles
•3. Must be planning a second full IVF/ICSI cycle
•4. Primary or secondary infertility
•5. Normal transvaginal ultrasound, defined as no visible intracavitary pathology or intramural myomas with impression of the uterine cavity
•6. Written informed consent

•1. History of lower abdominal or pelvic infection
•2. Higher chance of intra-abdominal infection due to intestinal surgery (for for instance Crohn*s disease or colitis)
•3. Endometriosis grade 3 and 4
•4. Previous caesarean section with niche formation
•5. The presence of untreated unilateral or bilateral hydrosalpinx
•6. Previous endometrial scratching
•7. Meno-metrorrhagia (defined as any intermenstrual loss of blood)
•8. Oocyte donation cycles
•9. Pre-implantation genetic diagnosis (PGD) cycles
•10. Medical contra-indication for IVF/ICSI
•11. Untreated/unsubstituted endocrine abnormalities (e.g. pituitary, thyroid, adrenal or pancreas)

发起方

niversitair Medisch Centrum Utrecht