Brain Interaction of Cognition and Emotion in Patients with Schizophrenia: experiments in search of a common brain mechanism using functional magnetic resonance imaging (fMRI)

Recruiting

• Conditions: psychosis; Schizophrenia; 10039628

• Registration Number: NL-OMON30747
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 75

Inclusion Criteria

All patients (treated with clozapine or haloperidol or untreated) with a diagnosis of *first episode psychosis*, suggestive for the diagnosis schizophrenia are eligible to participate in the study. Age between 18 and 40 years

Exclusion Criteria

Any neurological, cardiovascular, and respiratory diseases; claustrophobia, pregnancy; other relevant psychiatric disorders; MRI contraindications. Subjects will also be excluded when they cannot understand the Dutch language sufficiently to understand the purposes and implications of the experiment.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Group differences in pattern or intensity of activation between the group of<br /><br>patients and healthy controls as measured by fMRI. Influence of medication on<br /><br>pattern or intensity of activation in the group of patients with schizophrenia</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>None.</p><br>