Feasibility study of intratumoral gold marker placement and cone beam CT for image- guided radiotherapy in rectal cancer

Withdrawn

• Conditions: rectal cancer; 10017991

• Registration Number: NL-OMON38849
• Lead Sponsor: Medisch Universitair Ziekenhuis Maastricht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- Patients with histological or cytological proven rectal cancer, treated with long course external beam radiotherapy (both conformal and IMRT radiation therapy techniques are allowed)
- Age ><= 18 years
- Have given written informed consent before patient registration

Exclusion Criteria

Patients using anticoagulants (platelet aggregation inhibitors and coumarines)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary endpoint is the concordance index between observers on kV CBCT</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints:<br /><br>- % of marker loss<br /><br>- intra-observer variation in GTV localization with and without markers<br /><br>- tumor movement<br /><br>- use of goldmarkers for automatic online matching<br /><br>- development of SIB technique</p><br>