The effect of short term excess dietary fat, carbohydrate or energy on liver fat content in healthy women.

Not Applicable

Recruiting

• Conditions: on-alcoholic fatty liver disease; Non-alcoholic fatty liver disease; Diet and Nutrition - Other diet and nutrition disorders; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12616000613404
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-11
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 12

Inclusion Criteria

* healthy non-smoking women aged 20-55 years
* normal weight (defined as body mass index (BMI) 20-25kg/m2)
* healthy liver (defined as normal liver enzymes and normal liver imaging (ultrasound))
* Dunedin (New Zealand) city residents

Exclusion Criteria

* any liver disease including NAFLD
* consume more than 14 standard units of alcohol per week
* diabetes or prediabetes
* pregnancy
* lactating
* postmenopausal
* taking recreational drugs or medication that potentially affects the liver
* dietary intolerances or food allergies
* contraindications to H-MRS radiological examination including claustrophobia

Study & Design

• Study Type: Interventional
• Study Design: Not specified