In extremely low birth weight (ELBW) infants who require positive pressure at birth does the Neopuff Infant Resuscitator compared with the Laerdal Infant Bag improve oxygen saturation measurements in the first ten minutes of life?
Completed
- Conditions
- Oxygen saturation in the first ten minutes of life in infants born at less than 29 weeks gestation who require positive pressure ventilationReproductive Health and Childbirth - Childbirth and postnatal care
- Registration Number
- ACTRN12607000062426
- Lead Sponsor
- Professor Colin J Morley
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 76
Inclusion Criteria
All infants born <29 weeks gestation in need of positive pressure ventilation, because of inadequate respiration and/or a heart rate of less than one hundred beats per minute (HR <100 bpm) will be eligible for resuscitation and therefore entry to this study.
Exclusion Criteria
Infants will be excluded from final analysis if they have a condition that might have an adverse effect on breathing or ventilation apart from prematurity or asphyxia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The difference in oxygenation saturation from the first measurement soon after birth until 10 minutes of age.[Measured soon after birth until 10 minutes of age]
- Secondary Outcome Measures
Name Time Method 1. Time for heart rate to rise above 100 bpm[Measured soon after birth until 10 minutes of age.];2. Incidence of intubation and ventilation in the first 24 hours of life.[Measured at 24 hours of age.];3. Tidal volumes delivered during the first 10 minutes of life[Measured soon after birth until 10 minutes of age.];4. To determine whether the response to each device varies with:<br>a. gestational age<br>b. type of birth (vaginal or caesarean)<br>c. absence/presence of labour<br>d. antenatal steroids[Measured soon after birth until 10 minutes of age.]