The Effectiveness of Clomiphene Citrate In suppression of Luteinising Hormone (LH) Surge in Assisted Reproductive Technologies (ART): A randomized controlled pilot study

Not Applicable

• Conditions: Subfertile couples; Mild male factor; Reproductive Health and Childbirth - Fertility including in vitro fertilisation

• Registration Number: ACTRN12607000568415
• Lead Sponsor: Hesham G. Al-Inany, MD, PhD

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-11-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

mild male factor
-less than 39 years of age
- Normal uterus as documented by ultrasound (US) examination
- healthy females as documented by examination and laboratory tests

Exclusion Criteria

- Subfertility due to other causes
- Any significant cardiovascular, pulmonary, neurologic, allergic, hepatic or renal disease
- Any laboratory parameter clinically relevant outside the normal range
- No ovarian cyst formation >2cm prior to start of stimulation
- Women with Body Mass Index (BMI) > 30
- Women with Polycystic Ovary (PCO) Syndrome

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
H surge[- First visit (clinical examination, medical history, determine inclusion/ exclusion criteria, patient signs the consent form and is randomized)<br>- Serum LH and adverse events will be determined and recorded at regular follow-up visits according to patient response]

Secondary Outcome Measures

Name	Time	Method
endometrial thickness on day of hCG[- Determined on the day of hCG administration]