Prevention of lymphoedema after clearance by external compressio

Not Applicable

Completed

• Conditions: Topic: National Cancer Research Network; Subtopic: Breast Cancer; Disease: Breast; Cancer; Breast cancer

• Registration Number: ISRCTN92355292
• Lead Sponsor: niversity Hospital of South Manchester (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-10-28
• Study Completion: 2015-04-01
• Last Update Posted: 3 August 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 270

Inclusion Criteria

1. Women aged 18 - 90 years
2. Early breast cancer (no evidence of metastatic disease by local screening procedures), scheduled to undergo axillary node clearance
3. Consented to pre-surgical arm measurements by perometer and develop arm volume increases of 4 - 8.9% within 6 months after surgery
4. Willing to attend for follow-up visits per the trial schedule
5. Written informed consent to enter the PLACE trial

Exclusion Criteria

1. Any patients with no pre-surgical baseline measurements
2. Known distant metastasis
3. Inoperable breast cancer (T4 category or distant metastasis)
4. Node negative not undergoing axillary clearance
5. Previous axillary radiotherapy
6. Past history of breast/chest wall radiotherapy
7. Previous axillary clearance, either unilateral or bilateral
8. Participation in another clinical trial of local therapy that may affect the results obtained in this study
9. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified