Healing Rates After Single Versus Multiple Visits Endodontic Treatment of Necrotic Teeth With Apical Periodontitis: A Randomized Clinical Trial
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 44
- 主要终点
- postoperative pain
研究概览
简要总结
Healing rate after single visit or multiple visit endodontic treatment using triple paste intracanal medicament will be assessed both clinically and radio-graphically for follow-up period up to one year
详细描述
Patients with necrotic teeth with apical periodontitis will be selected according to the eligibility criteria and patients are then randomized to either single visit or multiple visit using triple paste intracanal medicament. Postoperative pain will then assessed using numerical rating scale after 1, 2, 3 and 7 days post-instrumentation. Radiographic healing will be assessed every 3 months up to one year.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 16 Years 至 55 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients; age between 16-55 years old.
- •Males or Females.
- •Maxillary or mandibular single-root tooth or a multi-rooted tooth with:
- •Non-vital response of pulp tissue.
- •Radiographic evidence of periapical lesions (minimum size 2.0 mm × 2.0 mm) related to one root in case of multi-rooted teeth.
- •Asymptomatic patients.
- •Positive patients' acceptance for participation in the study.
排除标准
- •Primary teeth, and permanent teeth with immature apex.
- •Teeth previously accessed or endodontically treated.
- •Patients with diabetes and immune-compromising disease.
- •Patients allergic to metronidazole, ciprofloxacin, or minocycline.
- •Vital cases or necrotic without periapical lesion.
- •Pregnant women.
- •Teeth with unfavorable conditions for rubber-dam application.
- •Tooth associated with vertical root fracture, coronal perforation, calcification and external or internal root resorption.
研究组 & 干预措施
multiple visit
multiple visit root canal treatment with triple antibiotic paste intracanal medication (a mixture of metronidazole, ciprofloxacin, and minocycline)
干预措施: mixture of metronidazole, ciprofloxacin, and minocycline (Drug)
结局指标
主要结局
postoperative pain
时间窗: 7 days
using numerical rating scale from 0-10
次要结局
- Radiographic healing(12 months)
研究者
Safeya AbdelRahaman Hassan
Assistant lecturer
Cairo University