The efficacy of neutralizing heparin by prothamine in cardiac open heart surgery
Phase 2
- Conditions
- Heart disease.Atherosclerosis
- Registration Number
- IRCT20180719040524N1
- Lead Sponsor
- Rajaie Heart Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients who do not have an anticoagulant drug
Patients undergoing surgery for the first time
Exclusion Criteria
Patients with a history of heart surgery
Patients with coagulation disorders
Patients with liver and kidney failure
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To investigate more precisely the blood factors and the results of neutralizing the effects of anticoagulant drugs used during surgery, we use the ROTEM device. Timepoint: At the end of the operation, if necessary, an observer will be used. Method of measurement: By ROTEM.;Our primary variable is the patient's activated clotting time (ACT). Timepoint: ACT is taken from the beginning of the surgery every hour and ACT is taken at the end of the operation, after neutralizing the effect of heparin ACT. Method of measurement: Measured by ACT.
- Secondary Outcome Measures
Name Time Method